Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 8/20 | 0.46 |
| ▸ | F10 | P00742 | 8/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | MMP8 | P22894 | 2/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7079926 | 0.88 | MAOA (0.48) | F10MAOAMAOBALDH1A1CYP19A1 | |
| SCHEMBL7079158 | 0.86 | SMN1; SMN2 (0.43) | F2F10PRSS1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7075400 | 0.84 | F2 (0.45) | F2F10PRSS1ALDH1A1MMP2 | |
| SCHEMBL7077585 | 0.83 | F2 (0.41) | F2F10PRSS1ALDH1A1MMP2 | |
| SCHEMBL7077837 | 0.82 | ALDH1A1 (0.45) | F2F10PRSS1ALDH1A1PRMT1 | |
| SCHEMBL7078814 | 0.80 | MMP13 (0.48) | F2F10PRSS1ALDH1A1MMP2 | |
| SCHEMBL7073767 | 0.79 | MMP13 (0.49) | F2F10PRSS1ALDH1A1MMP2 | |
| SCHEMBL7073376 | 0.79 | ALDH1A1 (0.46) | F2F10PRSS1ALDH1A1MMP2 | |
| SCHEMBL7073328 | 0.79 | ALDH1A1 (0.40) | F2F10PRSS1ALDH1A1 | |
| SCHEMBL7074301 | 0.78 | AOC3 (0.39) | F2F10PRSS1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003059872-A1 | AVB3 AND AVB5 INTEGRIN ANTAGONISTS AND METHODS OF TREATING DISEASES OR CONDITIONS ASSOCIATED WITH AVB3 AND AVB5 INTEGRINS | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-07-24 | — | — | WO | disclosed |