SCHEMBL7073794

SCHEMBL7073794

O=Cc1ccc(OCc2ccccc2)c(Cc2c(OCc3ccccc3)ccc(C=O)c2-c2ccc(OCc3ccccc3)cc2)c1

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAOA P21397 7/20 0.48
MAOB P27338 7/20 0.48
RAB9A P51151 2/20 0.41
LCK P06239 1/20 0.41
GSTP1 P09211 1/20 0.41
PTPN1 P18031 2/20 0.40
NPC1 O15118 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
ERN1 O75460 2/20 0.39
GSK3B P49841 1/20 0.38
BACE1 P56817 1/20 0.38
CCNB2 O95067 1/20 0.37
CDK1 P06493 1/20 0.37
CDK4 P11802 1/20 0.37
CCNB1 P14635 1/20 0.37
CCND1 P24385 1/20 0.37
CCNB3 Q8WWL7 1/20 0.37
ALDH1A1 P00352 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL978216 0.79 MAOA (0.60) MAOAMAOBRAB9ANPC1CCNB2
SCHEMBL5213883 0.78 MAOA (0.68) MAOAMAOBRAB9ALCKNPC1
SCHEMBL7071776 0.76 ERN1 (0.42) ERN1ALDH1A1
SCHEMBL7067338 0.76 GAA (0.39) MAOAMAOBERN1ALDH1A1
SCHEMBL7069599 0.76 CYP1A2 (0.44) RAB9ANPC1TDP1ERN1ALDH1A1
SCHEMBL1897186 0.73 MAOA (0.59) MAOAMAOBRAB9ANPC1TDP1
SCHEMBL865350 0.73 MAOA (0.58) MAOAMAOBRAB9ALCKPTPN1
SCHEMBL3615463 0.73 MAOB (0.58) MAOAMAOBRAB9ALCKGSTP1
SCHEMBL31312392 0.73 MAOA (0.58) MAOAMAOBRAB9APTPN1NPC1
SCHEMBL6187222 0.72 RAB9A (0.62) MAOAMAOBRAB9ALCKGSTP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030092685-A1 Compounds, compositions and methods for treating or preventing pneumovirus infection and associated diseases NITZ THEODORE J (US) 2003-05-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030092685-A1 Compounds, compositions and methods for treating or preventing pneumovirus infection and associated diseases TTPA, HAVCR2, PML MAOA 3178/4885MAOB 2227/4885RAB9A 2880/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.