Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7073794 | 0.76 | MAOA (0.48) | ALDH1A1ERN1NPC1RAB9ATDP1 | |
| SCHEMBL24489133 | 0.72 | ALDH1A1 (0.65) | CYP1A2ALDH1A1TSHRCYP2A6MAPT | |
| SCHEMBL28803580 | 0.72 | ALDH1A1 (0.53) | CYP1A2ALDH1A1ERN1CYP2A6MAPT | |
| SCHEMBL13078747 | 0.71 | ERN1 (0.60) | CYP1A2ALDH1A1ERN1LMNACYP2C9 | |
| SCHEMBL3920869 | 0.70 | ALDH1A1 (0.58) | ALDH1A1ERN1TSHRCYP2A6MAPT | |
| SCHEMBL7072441 | 0.70 | ERN1 (0.46) | ALDH1A1ERN1MAPTMEN1HPGD | |
| SCHEMBL29957052 | 0.70 | ALDH1A1 (0.66) | CYP1A2ALDH1A1TSHRMAPTRXFP1 | |
| SCHEMBL2432443 | 0.70 | ALDH1A1 (0.66) | CYP1A2ALDH1A1TSHRMAPTRXFP1 | |
| SCHEMBL2871306 | 0.69 | NPC1 (0.52) | CYP1A2ALDH1A1TSHRCYP2A6MAPT | |
| 3,4-Dimethoxybenzaldehyde SCHEMBL17888881 | 0.68 | ALDH1A1 (0.81) | CYP1A2ALDH1A1TSHRCYP2A6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030092685-A1 | Compounds, compositions and methods for treating or preventing pneumovirus infection and associated diseases | NITZ THEODORE J (US) | 2003-05-15 | — | — | US | disclosed |
| US-6495580-B1 | A BENZYLIDENE DERIVATIVE CONTAINING HETEROCYCLIC RING IS USEFUL AS PNEUMOVIRUS INHIBITOR | VIROPHARMA INCORPORATED | 2002-12-17 | — | — | US | disclosed |
| EP-1051169-A4 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING PNEUMOVIRUS INFECTION AND ASSOCIATED DISEASES | VIROPHARMA INC (US) | 2002-05-29 | — | — | EP | disclosed |
| EP-1051169-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING PNEUMOVIRUS INFECTION AND ASSOCIATED DISEASES | Viropharma Incorporated (US) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999038508-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING PNEUMOVIRUS INFECTION AND ASSOCIATED DISEASES | VIROPHARMA INCORPORATED (US) | 1999-08-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030092685-A1 | Compounds, compositions and methods for treating or preventing pneumovirus infection and associated diseases | TTPA, HAVCR2, PML | CYP1A2 1085/4885ALDH1A1 3369/4885ERN1 3269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.