Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CCNC | P24863 | 1/20 | 0.44 |
| ▸ | CDK8 | P49336 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7076841 | 0.89 | MGLL (0.54) | LMNAHPGDHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL7648133 | 0.88 | MAPT (0.59) | LMNAHPGDHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL7070524 | 0.87 | STAT3 (0.52) | LMNAHPGDHTT | |
| SCHEMBL7073874 | 0.86 | MAPT (0.52) | LMNAHPGDHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL7071875 | 0.80 | MAPT (0.51) | LMNAHPGDHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL7070301 | 0.80 | MGLL (0.52) | LMNAHPGDALDH1A1POLBMGLL | |
| SCHEMBL7077120 | 0.79 | MGLL (0.47) | LMNAMGLLTSHRNFKB1RAB9A | |
| SCHEMBL7071622 | 0.78 | SMYD3 (0.50) | LMNAMEN1KMT2AMGLL | |
| SCHEMBL7074195 | 0.78 | HPGD (0.54) | HPGDALDH1A1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL7069983 | 0.78 | LMNA (0.58) | LMNAHTTALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025086-B1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-25 | — | — | EP | disclosed |