Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.54 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7074246 | 0.89 | LMNA (0.52) | MGLLLMNAHTTHPGDGAA | |
| SCHEMBL7070524 | 0.88 | STAT3 (0.52) | LMNAHTTHPGDHDAC4HDAC2 | |
| SCHEMBL7073874 | 0.87 | MAPT (0.52) | MGLLLMNAHTTHPGDHDAC4 | |
| SCHEMBL7649408 | 0.86 | DGAT1 (0.58) | MGLLDGAT1LMNAHDAC4GAA | |
| SCHEMBL7070301 | 0.86 | MGLL (0.52) | MGLLDGAT1LMNAHPGDHDAC4 | |
| SCHEMBL7071875 | 0.86 | MAPT (0.51) | MGLLLMNAHTTHPGDGAA | |
| SCHEMBL7074772 | 0.83 | MGLL (0.66) | MGLLDGAT1LMNAHPGDHDAC4 | |
| SCHEMBL7077120 | 0.81 | MGLL (0.47) | MGLLDGAT1LMNAHDAC4PLK1 | |
| SCHEMBL7071622 | 0.80 | SMYD3 (0.50) | MGLLLMNAHDAC4PLK1HDAC2 | |
| SCHEMBL7074106 | 0.78 | HDAC4 (0.58) | MGLLDGAT1LMNAHTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025086-B1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-25 | — | — | EP | disclosed |