Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | FNTA | P49354 | 1/20 | 0.59 |
| ▸ | FNTB | P49356 | 1/20 | 0.59 |
| ▸ | F2 | P00734 | 1/20 | 0.57 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.57 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.57 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.57 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | GPR183 | P32249 | 1/20 | 0.52 |
| ▸ | ME2 | P23368 | 1/20 | 0.52 |
| ▸ | ME1 | P48163 | 1/20 | 0.52 |
| ▸ | ME3 | Q16798 | 1/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28743988 | 0.95 | CYP2C9 (0.55) | CYP2C9CYP2C19FNTAFNTBF2 | |
| SCHEMBL16599088 | 0.84 | GPR183 (0.73) | CYP2C9CYP2C19FNTAFNTBGFER | |
| SCHEMBL7075152 | 0.78 | CNR1 (0.51) | CYP2C19F2PRSS1TPSAB1TPSD1 | |
| SCHEMBL7074218 | 0.76 | ALDH1A1 (0.67) | F2PRSS1TPSAB1TPSD1TPSG1 | |
| SCHEMBL10722382 | 0.76 | POLB (0.81) | GPR183POLBALDH1A1GAAKMT2A | |
| SCHEMBL9585721 | 0.76 | POLB (0.81) | GPR183POLBALDH1A1GAAKMT2A | |
| SCHEMBL7077553 | 0.75 | F10 (0.65) | POLBKMT2AMEN1LMNAMAPT | |
| SCHEMBL7430480 | 0.75 | HPGD (0.67) | CYP2C9CYP2C19GFERATMGPR183 | |
| SCHEMBL7069339 | 0.74 | CNR1 (0.55) | F2PRSS1TPSAB1TPSD1TPSG1 | |
| SCHEMBL7838912 | 0.74 | BLM (0.71) | FNTAFNTBGPR183POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025086-B1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-25 | — | — | EP | disclosed |
| US-6492368-B1 | Benzamidine derivatives as factor XA inhibitors | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |