SCHEMBL7074417

SCHEMBL7074417

CC(C)(C)c1cc(Oc2ccc(NC(=O)c3cccc(NC=O)c3O)cc2)cc(C(C)(C)C)c1

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 5/20 0.49
RXFP1 Q9HBX9 2/20 0.45
PNLIP P16233 5/20 0.44
MAPK1 P28482 1/20 0.43
GFER P55789 1/20 0.43
RAF1 P04049 1/20 0.42
TP53 P04637 1/20 0.42
AR P10275 1/20 0.42
TLR7 Q9NYK1 2/20 0.41
LMNA P02545 1/20 0.41
PLG P00747 1/20 0.41
KLKB1 P03952 1/20 0.41
KLK1 P06870 1/20 0.41
KLK6 Q92876 1/20 0.41
STK39 Q9UEW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7073943 0.93 PKM (0.47) RXFP1PNLIPMAPK1GFERTP53
SCHEMBL7078360 0.85 MAPT (0.44) RXFP1MAPK1RAF1TP53PLG
SCHEMBL7080494 0.85 PNLIP (0.62) PNLIPMAPK1GFERTP53AR
SCHEMBL7077257 0.84 RXFP1 (0.60) TLR8RXFP1RAF1TLR7STK39
SCHEMBL7074399 0.84 PNLIP (0.61) RXFP1PNLIPMAPK1GFERLMNA
SCHEMBL8629300 0.76 RXFP1 (0.48) TLR8RXFP1MAPK1RAF1TLR7
SCHEMBL7077402 0.76 PNLIP (0.43) PNLIPMAPK1GFERTP53LMNA
SCHEMBL1457071 0.75 RXFP1 (0.56) RXFP1TP53LMNA
SCHEMBL7078518 0.75 PNLIP (0.41) RXFP1PNLIPMAPK1GFERTP53
SCHEMBL7074805 0.74 PNLIP (0.67) PNLIPSTK39

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0848700-B1 ACYLAMINOSALICYLIC ACID AMIDES AND THEIR USES AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2003-07-02 EP claimed
EP-0848700-B1 ACYLAMINOSALICYLIC ACID AMIDES AND THEIR USES AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2003-07-02 EP disclosed
US-6548549-B1 Fungicides, insecticides, bactericides; applying to plant BAYER AKTIENGESELLSCHAFT (DE) 2003-04-15 US disclosed
US-6001879-A SUITABLE FOR CONTROLLING PESTS, PREFERABLY FUNGI, INSECTS AND BACTERIA, IN PLANTS AND INDUSTRIAL MATERIALS; METHODS OF THEIR SYBNTHESIS INCLUDING REACTING AMINOSALICYLAMIDES WITH ACYLATING AGENTS BAYER AKTIENGESELLSCHAFT (DE) 1999-12-14 US disclosed
EP-0848700-A1 ACYLAMINOSALICYLIC ACID AMIDES AND THEIR USES AS PESTICIDES BAYER AG (DE) 1998-06-24 EP disclosed
WO-1997008135-A1 ACYLAMINOSALICYLIC ACID AMIDES AND THEIR USES AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-03-06 WO disclosed