Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7080488 | 0.89 | NAALAD2 (0.35) | KMT2ANAALAD2MAPTALDH1A1 | |
| SCHEMBL12145025 | 0.71 | GABRP (0.39) | NAALAD2 | |
| SCHEMBL13840852 | 0.70 | NAALAD2 (0.42) | NAALAD2 | |
| SCHEMBL10492478 | 0.67 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL14102937 | 0.67 | NAALAD2 (0.57) | NAALAD2 | |
| SCHEMBL7074520 | 0.67 | MEN1 (0.32) | MEN1TSHRKMT2ABIRC2RECQL | |
| SCHEMBL17242795 | 0.66 | CYSLTR2 (0.36) | MEN1TSHRKMT2AALDH1A1 | |
| SCHEMBL6954475 | 0.66 | NAALAD2 (0.43) | NAALAD2 | |
| SCHEMBL17242863 | 0.65 | GABRP (0.34) | NAALAD2 | |
| SCHEMBL25600174 | 0.65 | TSHR (0.50) | MEN1TSHRKMT2ABIRC2RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758328-B1 | ANTI-CANCER COMPOUNDS CONTAINING CYCLOPENTAQUINAZOLINE RING | BTG INT LTD (GB) | 2003-07-16 | — | — | EP | disclosed |