Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29946603 | 1.00 | PTPN22 (0.47) | PTPN22POLBMEN1KMT2AKDM4E | |
| SCHEMBL3075110 | 0.79 | ALDH1A1 (0.39) | POLBMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL2482183 | 0.79 | ALDH1A1 (0.39) | POLBMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL977301 | 0.79 | ALDH1A1 (0.39) | POLBMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL26370800 | 0.79 | PTPN22 (0.56) | PTPN22POLBMEN1KMT2AKDM4E | |
| SCHEMBL28666704 | 0.77 | PTPN22 (0.54) | PTPN22POLBMEN1KMT2AKDM4E | |
| SCHEMBL29946505 | 0.77 | MAPT (0.50) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL28915745 | 0.76 | PTPN22 (0.48) | PTPN22POLBMEN1KMT2AKDM4E | |
| SCHEMBL29946518 | 0.76 | PTPN22 (0.57) | PTPN22POLBMEN1KMT2AKDM4E | |
| SCHEMBL11756082 | 0.75 | PTPN22 (0.47) | PTPN22MEN1KMT2AALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030144524-A1 | With an aromatic derivative carrying at least one hydroxyl functional group, wherein the electron-withdrawing group present on the carbonyl compound is selected from fluoroalkyl derivatives, esters, including orthoesters, and nitriles and | RHODIA CHIMIE, FRANCE | 2003-07-31 | — | — | US | disclosed |
| US-6541674-B2 | Electron-withdrawing group present on carbonyl compound is selected from fluoroalkyl derivatives, esters, including orthoesters, and nitrites and condensation is carried out in basic medium | RHODIA CHIMIE (FR) | 2003-04-01 | — | — | US | disclosed |
| US-20010004670-A1 | Process for the condensation of a carbonyl compound with an aromatic derivative in a basic medium | RHODIA CHIMIE (FR) | 2001-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010004670-A1 | Process for the condensation of a carbonyl compound with an aromatic derivative in a basic medium | NCAPH, ODC1, NCAPD2 | PTPN22 3764/4885POLB 997/4885MEN1 1088/4885 |
| US-20030144524-A1 | With an aromatic derivative carrying at least one hydroxyl functional group, wherein the electron-withdrawing group present on the carbonyl compound is selected from fluoroalkyl derivatives, esters, including orthoesters, and nitriles and | ECE2, HCN4, ETV6 | PTPN22 2722/4885POLB 2980/4885MEN1 1940/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.