Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2482183 | 1.00 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2AHSD17B10CYP1A2 | |
| SCHEMBL977301 | 1.00 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2AHSD17B10CYP1A2 | |
| SCHEMBL8745296 | 0.87 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2AHSD17B10CYP1A2 | |
| SCHEMBL14155951 | 0.85 | MEN1 (0.37) | ALDH1A1MEN1KMT2AHSD17B10CYP1A2 | |
| SCHEMBL7074543 | 0.79 | PTPN22 (0.47) | ALDH1A1MEN1KMT2AHSD17B10CYP1A2 | |
| SCHEMBL29946603 | 0.79 | PTPN22 (0.47) | ALDH1A1MEN1KMT2AHSD17B10CYP1A2 | |
| SCHEMBL27925964 | 0.79 | L3MBTL1 (0.37) | ALDH1A1MEN1KMT2AHSD17B10CYP1A2 | |
| SCHEMBL14294943 | 0.78 | DHODH (0.32) | PTPN1DHODH | |
| SCHEMBL10132729 | 0.78 | DHODH (0.32) | PTPN1DHODH | |
| SCHEMBL488964 | 0.76 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AHSD17B10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11760750-B1 | Process for preparing levoketoconazole | NURAY CHEMICALS PRIVATE LIMITED (IN) | 2023-09-19 | — | — | US | claimed |
| EP-1299342-B1 | METHOD FOR PRODUCING 3,3-DIARYLPROPYLAMINES | SANOL ARZNEI SCHWARZ GMBH (DE) | 2007-05-02 | — | — | EP | claimed |
| CN-1269793-C | Process for producing 3, 3-diarylpropylamines | SANOL ARZNEI SCHWARZ GMBH (DE) | 2006-08-16 | — | — | CN | claimed |
| US-6809225-B2 | BY HYDROCARBONYLATION/HYDROFORMYLATION WITH SUBSEQUENT REDUCTIVE AMINATION | SCHWARZ PHARMA AG (DE) | 2004-10-26 | — | — | US | claimed |
| US-20040034080-A1 | Method for producing 3,3-diarylpropylamines | UCB PHARMA GMBH (DE) | 2004-02-19 | — | — | US | claimed |
| CN-1441771-A | Process for producing 3, 3-diarylpropylamines | SANOL ARZNEI SCHWARZ GMBH (DE) | 2003-09-10 | — | — | CN | claimed |
| EP-1299342-A1 | METHOD FOR PRODUCING 3,3-DIARYLPROPYLAMINES | SCHWARZ PHARMA AG (DE) | 2003-04-09 | — | — | EP | claimed |
| WO-2002004399-A1 | METHOD FOR PRODUCING 3,3-DIARYLPROPYLAMINES | SCHWARZ PHARMA AG (DE) | 2002-01-17 | — | — | WO | claimed |
| WO-2023173359-A1 | METABOLIC DISEASE THERAPEUTIC AGENT OR PREVENTIVE AGENT | 北京大学 | 2023-09-21 | — | — | WO | disclosed |
| US-11760750-B1 | Process for preparing levoketoconazole | NURAY CHEMICALS PRIVATE LIMITED (IN) | 2023-09-19 | — | — | US | disclosed |
| EP-3438113-B1 | TETRADENTATE LIGAND, AND PRODUCTION METHOD THEREFOR, SYNTHETIC INTERMEDIATE THEREOF, AND TRANSITION METAL COMPLEX THEREOF | TAKASAGO PERFUMERY CO LTD (JP) | 2021-02-17 | — | — | EP | disclosed |
| US-10731062-B2 | Gas-generating material and micropump | SEKISUI CHEMICAL CO., LTD. (JP) | 2020-08-04 | — | — | US | disclosed |
| EP-2860167-B1 | GAS GENERATING MATERIAL, AND MICROPUMP | SEKISUI CHEMICAL CO LTD (JP) | 2020-04-29 | — | — | EP | disclosed |
| US-10550141-B2 | Tetradentate ligand, and production method therefor, synthetic intermediate thereof, and transition metal complex thereof | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2020-02-04 | — | — | US | disclosed |
| WO-1991011449-A1 | PROCESS FOR THE PRODUCTION OF THIENOTRICYCLENE | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1991-08-08 | — | — | WO | disclosed |
| US-5004754-A | Biofungicidal composition | UNIVERSITE LAVAL (CA) | 1991-04-02 | — | — | US | disclosed |
| EP-0403252-A2 | Process for preparation of epoxy esters and intermediates prepared thereby | SMITHKLINE BEECHAM CORPORATION (US) | 1990-12-19 | — | — | EP | disclosed |
| US-4950761-A | Anticarcinogenic agent | SOUTHERN RESEARCH INSTITUTE (US) | 1990-08-21 | — | — | US | disclosed |
| EP-0336345-A2 | (2S)-(5-Amino-1,2-dihydro-2-methyl-3-phenylpyrido[3,4-b]pyrazin-7-yl)-carbamic acid, ethyl ester | Southern Research Institute (US) | 1989-10-11 | — | — | EP | disclosed |
| US-4866059-A | ANTICARCINOGENIC AGENTS; FUNGICIDES | WARNER-LAMBERT COMPANY (US) | 1989-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040034080-A1 | Method for producing 3,3-diarylpropylamines | HNMT, CYP1A1, HRH3 | ALDH1A1 121/4885MEN1 1298/4885KMT2A 207/4885 |
| US-10550141-B2 | Tetradentate ligand, and production method therefor, synthetic intermediate thereof, and transition metal complex thereof | CYP4F11, SLC39A11, CYP51A1 | ALDH1A1 970/4885MEN1 337/4885KMT2A 2986/4885 |
| US-11760750-B1 | Process for preparing levoketoconazole | KHK, KYAT3, PLK3 | ALDH1A1 2659/4885MEN1 2073/4885KMT2A 1550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.