Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | CHKA | P35790 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MC4R | P32245 | 1/20 | 0.47 |
| ▸ | MC5R | P33032 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7999722 | 0.88 | ALDH1A1 (0.45) | KMT2AALDH1A1MAPTTSHRLMNA | |
| SCHEMBL7071609 | 0.86 | NPC1 (0.65) | KMT2AALDH1A1MAPTTSHRLMNA | |
| SCHEMBL7074071 | 0.85 | KDM4E (0.56) | KMT2AALDH1A1MAPTTSHRLMNA | |
| SCHEMBL7996221 | 0.82 | PLA2G2A (0.42) | KMT2AALDH1A1MAPTTSHRLMNA | |
| SCHEMBL7073968 | 0.82 | MAPT (0.50) | KMT2AALDH1A1MAPTTSHRLMNA | |
| SCHEMBL28957460 | 0.82 | SMN1; SMN2 (0.63) | ALDH1A1MAPTTSHRLMNASMN1; SMN2 | |
| SCHEMBL5225958 | 0.82 | SMN1; SMN2 (0.59) | ALDH1A1MAPTTSHRLMNASMN1; SMN2 | |
| SCHEMBL5225149 | 0.81 | SMN1; SMN2 (0.61) | ALDH1A1MAPTTSHRLMNASMN1; SMN2 | |
| SCHEMBL5223197 | 0.80 | SMN1; SMN2 (0.53) | ALDH1A1MAPTTSHRLMNASMN1; SMN2 | |
| SCHEMBL5224880 | 0.80 | SMN1; SMN2 (0.62) | KMT2AALDH1A1MAPTTSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025086-B1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-25 | — | — | EP | disclosed |
| US-6492368-B1 | Benzamidine derivatives as factor XA inhibitors | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |