Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7076926 | 0.91 | LSS (0.52) | KDM4EALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL7070554 | 0.90 | MAPT (0.52) | KDM4EALDH1A1SLC2A1LMNASMN1; SMN2 | |
| SCHEMBL7069980 | 0.89 | TSHR (0.54) | ALDH1A1LMNASMN1; SMN2MAPTTSHR | |
| SCHEMBL7996072 | 0.86 | LMNA (0.46) | KDM4EALDH1A1GAALMNASMN1; SMN2 | |
| SCHEMBL7074835 | 0.85 | KMT2A (0.58) | ALDH1A1LMNASMN1; SMN2PKMHTT | |
| SCHEMBL7075159 | 0.85 | LSS (0.51) | ALDH1A1LMNASMN1; SMN2PKMHTT | |
| SCHEMBL7074079 | 0.85 | ALDH1A1 (0.63) | KDM4EALDH1A1LMNASMN1; SMN2PKM | |
| SCHEMBL7069977 | 0.85 | PKM (0.55) | KDM4EALDH1A1GAALMNASMN1; SMN2 | |
| SCHEMBL7074028 | 0.85 | MAPT (0.62) | KDM4ELMNASMN1; SMN2PKMHTT | |
| SCHEMBL7076863 | 0.84 | LSS (0.49) | ALDH1A1LMNASMN1; SMN2MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025086-B1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-25 | — | — | EP | disclosed |
| US-6492368-B1 | Benzamidine derivatives as factor XA inhibitors | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |