Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | GRK2 | P25098 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7079124 | 0.88 | ALDH1A1 (0.45) | KMT2AHSD11B1POLBGAAALDH1A1 | |
| SCHEMBL7074308 | 0.82 | MMP13 (0.45) | F2KMT2AHSD11B1GAAALDH1A1 | |
| SCHEMBL6774874 | 0.81 | F10 (0.43) | F2KMT2AHSD11B1GAAALDH1A1 | |
| SCHEMBL7077549 | 0.79 | DHODH (0.44) | ALDH1A1LMNAMMP8 | |
| SCHEMBL6264598 | 0.78 | F2 (0.50) | F2KMT2AALDH1A1F10LMNA | |
| SCHEMBL232194 | 0.78 | F2 (0.59) | F2KMT2AALDH1A1F10NPSR1 | |
| SCHEMBL7077769 | 0.77 | HSD17B10 (0.39) | F2KMT2AHSD11B1GAAALDH1A1 | |
| SCHEMBL7078046 | 0.77 | DHODH (0.42) | ALDH1A1LMNATSHRMMP8 | |
| SCHEMBL7078927 | 0.77 | CA12 (0.44) | F2KMT2AALDH1A1F10LMNA | |
| SCHEMBL31339242 | 0.76 | F2 (0.46) | F2KMT2AALDH1A1F10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003059872-A1 | AVB3 AND AVB5 INTEGRIN ANTAGONISTS AND METHODS OF TREATING DISEASES OR CONDITIONS ASSOCIATED WITH AVB3 AND AVB5 INTEGRINS | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-07-24 | — | — | WO | disclosed |