Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29857658 | 0.88 | GRM5 (0.41) | GRM5PDE10AP2RX7NPC1L3MBTL1 | |
| SCHEMBL3827608 | 0.88 | GRM5 (0.41) | GRM5PDE10AP2RX7NPC1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL28161689 | 0.86 | GRM5 (0.40) | GRM5PDE10AP2RX7NPC1L3MBTL1 | |
| SCHEMBL30720899 | 0.86 | TDP1 (0.46) | GRM5L3MBTL1 | |
| SCHEMBL31141498 | 0.86 | GRM5 (0.40) | GRM5PDE10AP2RX7NPC1L3MBTL1 | |
| SCHEMBL2995646 | 0.86 | TDP1 (0.46) | GRM5L3MBTL1 | |
| SCHEMBL4302902 | 0.84 | LIPG (0.49) | MAPTL3MBTL1 | |
| SCHEMBL29924070 | 0.84 | LIPG (0.49) | MAPTL3MBTL1 | |
| SCHEMBL10516875 | 0.84 | LIPG (0.49) | MAPTL3MBTL1 | |
| SCHEMBL19997559 | 0.84 | LIPG (0.49) | MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4925901-A | STORAGE STAABILITY, ONIUM ION CATALYST | THE DOW CHEMICAL COMPANY (US) | 1990-05-15 | — | — | US | claimed |
| JP-1308423-A | — | — | None | — | — | JP | disclosed |
| US-12503465-B2 | Process for preparing [3-chloro-2-[3-[2-[1-(2-chloroacetyl)-4-piperidyl]thiazol-4-yl]-4,5-dihydroisoxazol-5-yl]phenyl] methanesulfonate | BAYER AKTIENGESELLSCHAFT (DE) | 2025-12-23 | — | — | US | disclosed |
| EP-4077321-B1 | PROCESS FOR PREPARING [3-CHLORO-2-[3-[2-[1-(2-CHLOROACETYL)-4-PIPERIDYL]THIAZOL-4-YL]-4,5-DIHYDROISOXAZOL-5-YL]PHENYL] METHANESULFONATE | BAYER AG (DE) | 2025-06-25 | — | — | EP | disclosed |
| CN-114829360-B | Process for preparing Fluoxapiprolin intermediates | 拜耳公司 | 2025-03-07 | — | — | CN | disclosed |
| US-20230312587-A1 | PTERIDINONE COMPOUNDS AND USES THEREOF | VERTEX PHARMACEUTICALS INCORPORATED | 2023-10-05 | — | — | US | disclosed |
| EP-3265447-B1 | BENZOXAZINE LOW TEMPERATURE CURABLE COMPOSITION | HUNTSMAN ADVANCED MAT AMERICAS LLC (US) | 2023-03-01 | — | — | EP | disclosed |
| US-11572364-B2 | Pteridinone compounds and uses thereof | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-02-07 | — | — | US | disclosed |
| US-20230031599-A1 | PROCESS FOR PREPARING [3-CHLORO-2-[3-[2-[1-(2-CHLOROACETYL)-4-PIPERIDYL]THIAZOL-4-YL]-4,5-DIHYDROISOXAZOL-5-YL]PHENYL] METHANESULFONATE | BAYER AKTIENGESELLSCHAFT (DE) | 2023-02-02 | — | — | US | disclosed |
| EP-4077321-A1 | PROCESS FOR PREPARING [3-CHLORO-2-[3-[2-[1-(2-CHLOROACETYL)-4-PIPERIDYL]THIAZOL-4-YL]-4,5-DIHYDROISOXAZOL-5-YL]PHENYL] METHANESULFONATE | Bayer Aktiengesellschaft (DE) | 2022-10-26 | — | — | EP | disclosed |
| EP-0458502-B1 | Latent catalysts, cure-inhibited epoxy resin compositions and laminates prepared therefrom | DOW GLOBAL TECHNOLOGIES INC (US) | 2003-06-18 | — | — | EP | disclosed |
| EP-0328020-B1 | Use of a catalyst in epoxy compositions | DOW CHEMICAL CO (US) | 1996-10-09 | — | — | EP | disclosed |
| US-5503937-A | MIXTURE OF A COMPOUND HAVING MORE THAN ONE EPOXY GROUP, A DIHYDRIC PHENOLIC COMPOUND AND A LATENT CATALYST COMPRISING A SALT OF AN N-HETEROCYCLIC COMPOUND AND AN ACID HAVING A STRONG NUCLEOPHILIC ANION; COATINGS/MOLDINGS; STORAGE | THE DOW CHEMICAL COMPANY (US) | 1996-04-02 | — | — | US | disclosed |
| EP-0553887-A2 | Catalysts and epoxy resin composition containing the same | THE DOW CHEMICAL COMPANY (US) | 1993-08-04 | — | — | EP | disclosed |
| US-5169473-A | Complex of an onium, arsenic or amine compound and boric acid; advanced polyepoxides; storage stability | THE DOW CHEMICAL COMPANY (US) | 1992-12-08 | — | — | US | disclosed |
| US-5134239-A | Quaterinary indolizine compound | THE DOW CHEMICAL COMPANY (US) | 1992-07-28 | — | — | US | disclosed |
| EP-0458502-A2 | Latent catalysts, cure-inhibited epoxy resin compositions and laminates prepared therefrom | THE DOW CHEMICAL COMPANY (US) | 1991-11-27 | — | — | EP | disclosed |
| US-4925901-A | STORAGE STAABILITY, ONIUM ION CATALYST | THE DOW CHEMICAL COMPANY (US) | 1990-05-15 | — | — | US | disclosed |
| JP-H01308423-A | LATENT CATALYST AND EPOXY RESIN COMPOSITION CONTAINING IT | DOW CHEM CO:THE | 1989-12-13 | — | — | JP | disclosed |
| EP-0328020-A2 | Use of a catalyst in epoxy compositions | THE DOW CHEMICAL COMPANY (US) | 1989-08-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11572364-B2 | Pteridinone compounds and uses thereof | DPYD, PKD1, TYMP | GRM5 1533/4885PDE10A 1014/4885ADRA2A 4382/4885 |
| US-12503465-B2 | Process for preparing [3-chloro-2-[3-[2-[1-(2-chloroacetyl)-4-piperidyl]thiazol-4-yl]-4,5-dihydroisoxazol-5-yl]phenyl] methanesulfonate | CTPS2, DCPS, DHPS | GRM5 1322/4885PDE10A 2476/4885ADRA2A 1087/4885 |
| US-20230031599-A1 | PROCESS FOR PREPARING [3-CHLORO-2-[3-[2-[1-(2-CHLOROACETYL)-4-PIPERIDYL]THIAZOL-4-YL]-4,5-DIHYDROISOXAZOL-5-YL]PHENYL] METHANESULFONATE | CTPS2, DCPS, DHPS | GRM5 1322/4885PDE10A 2476/4885ADRA2A 1087/4885 |
| US-20230312587-A1 | PTERIDINONE COMPOUNDS AND USES THEREOF | DPYD, PKD1, TYMP | GRM5 1533/4885PDE10A 1014/4885ADRA2A 4382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.