SCHEMBL70758

SCHEMBL70758

[c]1c2ccccc2cc2c1c1ccccc1c1ccccc21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
HSD17B10 Q99714 3/20 0.39
HIF1A Q16665 1/20 0.39
CYP1B1 Q16678 1/20 0.39
HPRT1 P00492 3/20 0.37
TRPM4 Q8TD43 1/20 0.35
CYP2A6 P11509 2/20 0.35
TSHR P16473 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CYP1A2 P05177 2/20 0.34
THRB P10828 1/20 0.34
HPGD P15428 1/20 0.34
POLB P06746 1/20 0.33
MAPT P10636 1/20 0.33
PKM P14618 1/20 0.33
RAD52 P43351 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33
PAX8 Q06710 1/20 0.31
HTR2A P28223 1/20 0.30
NQO1 P15559 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2846828 0.78 ALDH1A1 (0.44) ALDH1A1HSD17B10HIF1ACYP1B1HPRT1
SCHEMBL3756283 0.78 ALDH1A1 (0.35) ALDH1A1HSD17B10HIF1ACYP1B1CYP2A6
SCHEMBL509570 0.77 ALDH1A1 (0.37) ALDH1A1HSD17B10HIF1ACYP1B1CYP2A6
SCHEMBL12474905 0.77 ALDH1A1 (0.44) ALDH1A1HSD17B10HIF1ACYP1B1HPRT1
SCHEMBL2210849 0.76 HPRT1 (0.35) ALDH1A1HSD17B10HIF1ACYP1B1HPRT1
SCHEMBL17063470 0.76 HPRT1 (0.35) ALDH1A1HSD17B10HPRT1CYP2A6TSHR
SCHEMBL14718718 0.74 HPRT1 (0.54) ALDH1A1HSD17B10HIF1ACYP1B1HPRT1
SCHEMBL24252 0.73 CYP2A6 (0.41) ALDH1A1HSD17B10HIF1ACYP1B1CYP2A6
SCHEMBL525913 0.72 ALDH1A1 (0.54) ALDH1A1HSD17B10HIF1ACYP1B1HPRT1
SCHEMBL17222500 0.71 MAPT (0.39) ALDH1A1HSD17B10TSHRTDP1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11248011-B2 Phosphorus-based releasing agent, optical polymerizable composition comprising same and preparation thereof SKC CO., LTD. (KR) 2022-02-15 US claimed
EP-3010055-B1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO (JP) 2021-10-20 EP claimed
US-11038123-B2 Compound and organic electronic device using the same SHANGHAI NICHEM FINE CHEMICAL CO., LTD. (CN) 2021-06-15 US claimed
US-10937968-B2 Compound and organic electronic device using the same SHANGHAI NICHEM FINE CHEMICAL CO., LTD. (CN) 2021-03-02 US claimed
US-10797244-B2 Compound, material for organic electroluminescent element, organic electroluminescent element, and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2020-10-06 US claimed
US-10784446-B2 Compound, organic electroluminescence element material, organic electroluminescence element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2020-09-22 US claimed
US-20190341552-A1 COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME SHANGHAI NICHEM FINE CHEMICAL CO., LTD. (CN) 2019-11-07 US claimed
US-20190263846-A1 PHOSPHORUS-BASED RELEASING AGENT, OPTICAL POLYMERIZABLE COMPOSITION COMPRISING SAME AND PREPARATION THEREOF SK PUCORE CO., LTD. (KR) 2019-08-29 US claimed
EP-3530684-A1 PHOSPHORUS-BASED RELEASING AGENT, OPTICAL POLYMERIZABLE COMPOSITION COMPRISING SAME AND PREPARATION THEREOF SKC Co., Ltd. (KR) 2019-08-28 EP claimed
US-20180277772-A1 COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME NICHEM FINE TECHNOLOGY CO., LTD. (TW) 2018-09-27 US claimed
EP-1000070-A1 SILICON-CONTAINING CHAIN EXTENDERS CARDIAC CRC NOMINEES PTY. LTD. (AU) 2000-05-17 EP claimed
EP-0984997-A4 SILICON-BASED POLYCARBONATES CARDIAC CRC NOMINEES PTY LTD (AU) 2000-03-29 EP claimed
EP-0984997-A1 SILICON-BASED POLYCARBONATES CARDIAC CRC NOMINEES PTY. LTD. (AU) 2000-03-15 EP claimed
WO-1999003863-A1 SILICON-CONTAINING CHAIN EXTENDERS CARDIAC CRC NOMINEES PTY. LTD. (AU) 1999-01-28 WO claimed
WO-1998054242-A1 SILICON-BASED POLYCARBONATES CARDIAC CRC NOMINEES PTY. LTD. (AU) 1998-12-03 WO claimed
EP-0697387-B1 Improved method for the preparation of iodonium salts DOW CORNING (US) 1998-04-22 EP claimed
US-5624762-A Radiation curable compositions containing vinyl ether functional polyorganosiloxanes DOW CORNING CORPORATION (US) 1997-04-29 US claimed
US-5594042-A RELEASE AGENTS FOR PRESSURE SENSITIVE ADHESIVES DOW CORNING CORPORATION (US) 1997-01-14 US claimed
EP-0697387-A2 Improved method for the preparation of iodonium salts DOW CORNING CORPORATION (US) 1996-02-21 EP claimed
US-5426222-A Mixing iodoarene dicarboxylate, solvent, adding acid to form homogeneous reaction mixture, reacting with benzene or substituted benzene, stripping solvent DOW CORNING CORPORATION (US) 1995-06-20 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10797244-B2 Compound, material for organic electroluminescent element, organic electroluminescent element, and electronic device RER1, RBM12, H1-2 ALDH1A1 1176/4885HSD17B10 2839/4885HIF1A 1998/4885
US-20180277772-A1 COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME CHRM1, CHRM2, C1S ALDH1A1 994/4885HSD17B10 2250/4885HIF1A 3442/4885
US-10937968-B2 Compound and organic electronic device using the same CHRM1, CHRM2, C1S ALDH1A1 446/4885HSD17B10 1690/4885HIF1A 4492/4885
US-20190263846-A1 PHOSPHORUS-BASED RELEASING AGENT, OPTICAL POLYMERIZABLE COMPOSITION COMPRISING SAME AND PREPARATION THEREOF PMM2, PGM2, IPMK ALDH1A1 2995/4885HSD17B10 4204/4885HIF1A 3589/4885
US-11248011-B2 Phosphorus-based releasing agent, optical polymerizable composition comprising same and preparation thereof PMM2, PGM2, IPMK ALDH1A1 2995/4885HSD17B10 4204/4885HIF1A 3589/4885
US-10784446-B2 Compound, organic electroluminescence element material, organic electroluminescence element and electronic device L1CAM, SOD1, OR10J3 ALDH1A1 1412/4885HSD17B10 3199/4885HIF1A 1176/4885
US-20190341552-A1 COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME CHRM1, CHRM2, C1S ALDH1A1 446/4885HSD17B10 1690/4885HIF1A 4492/4885
US-11038123-B2 Compound and organic electronic device using the same CHRM1, CHRM2, C1S ALDH1A1 994/4885HSD17B10 2250/4885HIF1A 3442/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.