Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1835404 | 0.78 | MCL1 (0.36) | MCL1 | |
| SCHEMBL15657471 | 0.77 | MKNK1 (0.32) | MCL1 | |
| SCHEMBL15893192 | 0.72 | MCL1 (0.52) | MCL1 | |
| SCHEMBL15475264 | 0.72 | THRB (0.38) | — | |
| SCHEMBL10827651 | 0.72 | GLI1 (0.34) | — | |
| SCHEMBL134765 | 0.69 | MCL1 (0.62) | MCL1 | |
| SCHEMBL14173702 | 0.68 | ALDH1A1 (0.47) | — | |
| SCHEMBL6826709 | 0.67 | CYP1A2 (0.33) | — | |
| SCHEMBL5864679 | 0.67 | MAPK1 (0.41) | MCL1 | |
| SCHEMBL11215361 | 0.66 | KDM4E (0.40) | MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1116266-C | Process for preparation of acylated cyclic 1,3-dicarbonyl compounds | ZENECA LTD (GB) | 2003-07-30 | — | — | CN | disclosed |
| EP-1034159-B1 | PROCESS FOR THE PREPARATION OF ACYLATED CYCLIC 1,3-DICARBONYL COMPOUNDS | SYNGENTA LTD (GB) | 2003-01-22 | — | — | EP | disclosed |
| US-6218579-B1 | REARRANGEMENT OF CYCLOALKANONE ENOL ESTER IN PRESENCE OF AZOLE AND BASE | ZENECA LIMITED (GB) | 2001-04-17 | — | — | US | disclosed |
| WO-2000071785-A2 | 2-CYLCOALKYLCARBONYLCYCLOHEXANE-1,3-DIONE DERIVATIVES AS HERBICIDES | ZENECA LIMITED (GB) | 2000-11-30 | — | — | WO | disclosed |
| CN-1272837-A | Process for preparation of acylated cyclic 1,3-dicarbonyl compounds | ZENECA LTD (GB) | 2000-11-08 | — | — | CN | disclosed |
| EP-1034159-A1 | PROCESS FOR THE PREPARATION OF ACYLATED CYCLIC 1,3-DICARBONYL COMPOUNDS | ZENECA LIMITED (GB) | 2000-09-13 | — | — | EP | disclosed |
| WO-1999028282-A1 | PROCESS FOR THE PREPARATION OF ACYLATED CYCLIC 1,3-DICARBONYL COMPOUNDS | ZENECA LIMITED (GB) | 1999-06-10 | — | — | WO | disclosed |