Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 2/20 | 0.35 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ACLY | P53396 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3084515 | 0.85 | TSHR (0.46) | GABRR1GABRR2BLMGABRR3LMNA | |
| SCHEMBL3084517 | 0.85 | TSHR (0.46) | GABRR1GABRR2BLMGABRR3LMNA | |
| SCHEMBL712787 | 0.77 | TSHR (0.42) | GABRR1GABRR2BLMGABRR3LMNA | |
| SCHEMBL1538365 | 0.77 | TSHR (0.42) | GABRR1GABRR2BLMGABRR3LMNA | |
| SCHEMBL4600709 | 0.74 | THRB (0.40) | GABRR1GABRR2BLMGABRR3LMNA | |
| SCHEMBL447585 | 0.73 | THRB (0.55) | TSHRTHRBACLY | |
| SCHEMBL20625018 | 0.73 | TSHR (0.42) | GABRR1GABRR2BLMGABRR3LMNA | |
| SCHEMBL455399 | 0.72 | TSHR (0.46) | GABRR1GABRR2BLMGABRR3LMNA | |
| SCHEMBL14801551 | 0.72 | TSHR (0.46) | GABRR1GABRR2BLMGABRR3LMNA | |
| SCHEMBL63977 | 0.71 | THRB (0.58) | TSHRTHRBACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030194378-A1 | Novel aerosol formulation containing a polar fluorinated molecule | ASTRAZENECA AB (SE) | 2003-10-16 | — | — | US | disclosed |