Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 7/20 | 0.55 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.55 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.55 |
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7937253 | 0.80 | KEAP1 (0.41) | AKR1C3NPSR1AKR1C2 | |
| SCHEMBL7187290 | 0.80 | SLC5A1 (0.52) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| SCHEMBL18554686 | 0.79 | NPSR1 (0.48) | NPSR1ALDH1A1 | |
| SCHEMBL5165720 | 0.78 | AKR1B10 (0.54) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| SCHEMBL4117028 | 0.78 | HTT (0.67) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| SCHEMBL28523089 | 0.75 | NPSR1 (0.46) | NPSR1ALOX5NFKB1NFKB2RELA | |
| SCHEMBL7128585 | 0.75 | AKR1B10 (0.52) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| SCHEMBL5166422 | 0.75 | AKR1B10 (0.51) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| SCHEMBL10605759 | 0.74 | KEAP1 (0.36) | AKR1C3KMT2ANPSR1HPGDAKR1C2 | |
| SCHEMBL4854721 | 0.73 | THRA (0.49) | AKR1B1HTTNPSR1HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0867187-B1 | Propolis extract with improved water-solubility | HAYASHIBARA BIOCHEM LAB (JP) | 2003-07-09 | — | — | EP | claimed |
| EP-0867187-B1 | Propolis extract with improved water-solubility | HAYASHIBARA BIOCHEM LAB (JP) | 2003-07-09 | — | — | EP | disclosed |