SCHEMBL7937253

SCHEMBL7937253

C=CCc1cc(CCC(=O)O)cc(CC=C)c1O

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 0.41
FFAR1 O14842 3/20 0.39
NPSR1 Q6W5P4 1/20 0.39
PPARA Q07869 1/20 0.39
DHFR P00374 1/20 0.39
AKR1C3 P42330 1/20 0.37
AKR1C2 P52895 1/20 0.37
KDM4E B2RXH2 1/20 0.37
PCNA P12004 1/20 0.37
PTGDR Q13258 1/20 0.37
PTGDR2 Q9Y5Y4 1/20 0.37
GABRA1 P14867 2/20 0.37
GABRB2 P47870 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10605759 0.92 KEAP1 (0.36) KEAP1FFAR1NPSR1PPARADHFR
SCHEMBL6555050 0.85 GAA (0.48) NPSR1
SCHEMBL27448284 0.85 DHFR (0.38) NPSR1DHFRAKR1C3AKR1C2KDM4E
SCHEMBL11660801 0.83 GABRA1 (0.45) NPSR1DHFRKDM4EGABRA1GABRB2
SCHEMBL11278615 0.82 PTGDR (0.42) DHFRKDM4EPTGDRPTGDR2GABRA1
SCHEMBL8418481 0.82 GABRA1 (0.53) KEAP1FFAR1NPSR1PPARAKDM4E
SCHEMBL8756876 0.81 GAA (0.44) NPSR1
SCHEMBL11017537 0.81 AKR1C3 (0.39) DHFRAKR1C3AKR1C2KDM4EGABRA1
SCHEMBL8417745 0.81 KDM4E (0.41) DHFRAKR1C3AKR1C2KDM4EGABRA1
SCHEMBL7076885 0.80 AKR1C3 (0.55) NPSR1AKR1C3AKR1C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4999393-A Light and heat resistance; stabilizers with antioxidants ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1991-03-12 US claimed
US-3969530-A 4-Hydroxy-3,5-di-alkyl-phenyl-propionic acid composition suitable as lipid lowering and anti-diabetic agents HOECHST AKTIENGESELLSCHAFT (DT) 1976-07-13 US claimed
JP-6135897-A None JP disclosed
JP-1254769-A None JP disclosed
JP-58208287-A None JP disclosed
US-12024622-B2 Composition, thermoplastic resin composition using same, and molded article thereof ADEKA CORPORATION (JP) 2024-07-02 US disclosed
WO-2024053468-A1 CATALYTIC REACTION METHOD, METHOD FOR PRODUCING ORGANIC COMPOUND, AND CATALYST COMPOSITION 日東電工株式会社 2024-03-14 WO disclosed
US-20240043655-A1 ADDITIVE COMPOSITION, RESIN COMPOSITION, METHOD FOR PRODUCING RESIN COMPOSITION, AND MOLDED ARTICLE ADEKA CORPORATION (JP) 2024-02-08 US disclosed
US-11884809-B2 Molded article and laminate incorporating acrylic resin composition ADEKA CORPORATION (JP) 2024-01-30 US disclosed
US-20240010815-A1 CRYSTALLIZATION INHIBITOR FOR POLYOLEFIN RESIN, POLYOLEFIN RESIN COMPOSITION, MOLDED ARTICLE, METHOD FOR PRODUCING POLYOLEFIN RESIN COMPOSITION, AND METHOD FOR INHIBITING CRYSTALLIZATION OF POLYOLEFIN RESIN ADEKA CORPORATION (JP) 2024-01-11 US disclosed
EP-3527617-B1 POLYOLEFIN RESIN COMPOSITION AND MOLDED ARTICLE USING SAME ADEKA CORP (JP) 2023-11-29 EP disclosed
EP-0049575-A1 Process for the production of vinyl halide polymers TENNECO POLYMERS, INC. (US) 1982-04-14 EP disclosed
US-4324874-A CHAIN-TERMINATING AGENT TENNECO CHEMICALS, INC. (US) 1982-04-13 US disclosed
US-4305868-A Phenolic esteramide antioxidants UNIROYAL, INC. (US) 1981-12-15 US disclosed
US-4304714-A Polyfunctional phenolic oxamide antioxidants UNIROYAL, INC. (US) 1981-12-08 US disclosed
US-4263446-A Process for making 3-(3,5-dialkyl-4-hydroxyphenyl)propionate esters of hydroxyalkyloxamides UNIROYAL, INC. (US) 1981-04-21 US disclosed
US-4263446-A Process for making 3-(3,5-dialkyl-4-hydroxyphenyl)propionate esters of hydroxyalkyloxamides UNIROYAL, INC. (US) 1981-04-21 US disclosed
EP-0009866-A1 Phenolic esteramide antioxidants and their use UNIROYAL, INC. (US) 1980-04-16 EP disclosed
US-3969530-A 4-Hydroxy-3,5-di-alkyl-phenyl-propionic acid composition suitable as lipid lowering and anti-diabetic agents HOECHST AKTIENGESELLSCHAFT (DT) 1976-07-13 US disclosed
US-3969530-A 4-Hydroxy-3,5-di-alkyl-phenyl-propionic acid composition suitable as lipid lowering and anti-diabetic agents HOECHST AKTIENGESELLSCHAFT (DT) 1976-07-13 US disclosed