⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7078051 | 0.90 | MMP2 (0.30) | — | |
| SCHEMBL7217222 | 0.88 | MMP13 (0.38) | — | |
| SCHEMBL7074693 | 0.85 | — | — | |
| SCHEMBL7078959 | 0.76 | PLA2G7 (0.34) | — | |
| SCHEMBL7221727 | 0.70 | MMP2 (0.37) | — | |
| SCHEMBL7078769 | 0.69 | MMP2 (0.36) | — | |
| SCHEMBL6945448 | 0.67 | MMP2 (0.39) | — | |
| SCHEMBL7215123 | 0.67 | MMP2 (0.35) | — | |
| Hydrochloric Acid SCHEMBL7425983 | 0.67 | MMP2 (0.38) | — | |
| SCHEMBL7075518 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030207889-A1 | Hydroxamic and carboxylic acid derivatives having MMP and TNF inhibitory activity | OWEN DAVID ALAN (GB) | 2003-11-06 | — | — | US | disclosed |
| US-6566384-B1 | For therapy of cancer, inflammation and inflammatory diseases, tissue degeneration, periodontal disease, ophthalmological disease, dermatological disorders, fever, cardiovascular effects, haemorrhage, coagulation and acute phase response | DARWIN DISCOVERY LTD. (GB) | 2003-05-20 | — | — | US | disclosed |