Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7079094 | 0.82 | MEN1 (0.47) | ALDH1A1POLBMEN1KMT2ARAB9A | |
| SCHEMBL7073776 | 0.79 | ALDH1A1 (0.51) | ALDH1A1HPGDKMT2ALMNAMAPT | |
| SCHEMBL7079205 | 0.77 | ALDH1A1 (0.47) | ALDH1A1KMT2ALMNAL3MBTL1 | |
| SCHEMBL7077638 | 0.76 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1GAAPOLBMEN1 | |
| Fluoride SCHEMBL28190274 | 0.71 | ALDH1A1 (0.59) | ALDH1A1HPGDGAAPOLBCDC25B | |
| Methyl Carbamate SCHEMBL28105575 | 0.70 | CTSD (0.53) | SMN1; SMN2ALDH1A1HPGDGAAPOLB | |
| Methylsulfanylmethane SCHEMBL28313804 | 0.70 | ALDH1A1 (0.55) | ALDH1A1HPGDGAAPOLBCDC25B | |
| SCHEMBL11301800 | 0.69 | MAPK1 (0.59) | ALDH1A1HPGDGAAPOLBCDC25B | |
| Methyl Alcohol SCHEMBL27551657 | 0.69 | ALDH1A1 (0.56) | ALDH1A1HPGDGAAPOLBCDC25B | |
| Fluoride SCHEMBL28067846 | 0.69 | ALDH1A1 (0.57) | ALDH1A1HPGDGAAPOLBCDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003059872-A1 | AVB3 AND AVB5 INTEGRIN ANTAGONISTS AND METHODS OF TREATING DISEASES OR CONDITIONS ASSOCIATED WITH AVB3 AND AVB5 INTEGRINS | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-07-24 | — | — | WO | disclosed |