Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.40 |
| ▸ | ESRRB | O95718 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.38 |
| ▸ | F10 | P00742 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | FCER2 | P06734 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7073776 | 0.92 | ALDH1A1 (0.51) | ALDH1A1MTNR1AMTNR1BKCNA5F2 | |
| SCHEMBL7077638 | 0.88 | ALDH1A1 (0.46) | ALDH1A1MTNR1AMTNR1BKCNA5LMNA | |
| SCHEMBL7077861 | 0.87 | F2 (0.46) | ALDH1A1BACE1L3MBTL1F2F10 | |
| SCHEMBL7080815 | 0.84 | GABBR2 (0.51) | ALDH1A1MTNR1AMTNR1BBACE1LMNA | |
| SCHEMBL7259084 | 0.79 | ESR1 (0.50) | ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL7995142 | 0.79 | ALDH1A1 (0.67) | ALDH1A1KCNA5L3MBTL1KMT2A | |
| SCHEMBL7077633 | 0.77 | SMN1; SMN2 (0.40) | ALDH1A1L3MBTL1LMNAKMT2A | |
| SCHEMBL7073376 | 0.75 | ALDH1A1 (0.46) | ALDH1A1KCNA5ESRRBF2F10 | |
| SCHEMBL7239668 | 0.75 | ALDH1A1 (0.57) | ALDH1A1KCNA5L3MBTL1LMNAKMT2A | |
| SCHEMBL12268202 | 0.75 | ALDH1A1 (0.61) | ALDH1A1KCNA5L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003059872-A1 | AVB3 AND AVB5 INTEGRIN ANTAGONISTS AND METHODS OF TREATING DISEASES OR CONDITIONS ASSOCIATED WITH AVB3 AND AVB5 INTEGRINS | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-07-24 | — | — | WO | disclosed |
| WO-2003059872-A1 | AVB3 AND AVB5 INTEGRIN ANTAGONISTS AND METHODS OF TREATING DISEASES OR CONDITIONS ASSOCIATED WITH AVB3 AND AVB5 INTEGRINS | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-07-24 | — | — | WO | disclosed |