Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.48 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7079205 | 0.92 | ALDH1A1 (0.47) | ALDH1A1MTNR1AMTNR1BKCNA5KMT2A | |
| SCHEMBL7077638 | 0.90 | ALDH1A1 (0.46) | ALDH1A1MTNR1AMTNR1BKCNA5KMT2A | |
| SCHEMBL7995142 | 0.84 | ALDH1A1 (0.67) | ALDH1A1KCNA5KMT2APKMHPGD | |
| SCHEMBL10175188 | 0.81 | MTNR1A (0.54) | ALDH1A1MTNR1AMTNR1BKCNA5MAOA | |
| SCHEMBL554681 | 0.80 | MAOA (0.50) | ALDH1A1MTNR1AMTNR1BKMT2AMAOA | |
| SCHEMBL554680 | 0.80 | MAOA (0.50) | ALDH1A1MTNR1AMTNR1BKMT2AMAOA | |
| SCHEMBL22303151 | 0.79 | ALDH1A1 (0.57) | ALDH1A1KCNA5KMT2ALMNAFFAR1 | |
| SCHEMBL12268202 | 0.79 | ALDH1A1 (0.61) | ALDH1A1KCNA5KMT2AMAPT | |
| SCHEMBL7239668 | 0.79 | ALDH1A1 (0.57) | ALDH1A1KCNA5KMT2ALMNAFFAR1 | |
| SCHEMBL1811811 | 0.79 | ALDH1A1 (0.61) | ALDH1A1KCNA5KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003059872-A1 | AVB3 AND AVB5 INTEGRIN ANTAGONISTS AND METHODS OF TREATING DISEASES OR CONDITIONS ASSOCIATED WITH AVB3 AND AVB5 INTEGRINS | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-07-24 | — | — | WO | disclosed |
| WO-2003059872-A1 | AVB3 AND AVB5 INTEGRIN ANTAGONISTS AND METHODS OF TREATING DISEASES OR CONDITIONS ASSOCIATED WITH AVB3 AND AVB5 INTEGRINS | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-07-24 | — | — | WO | disclosed |