Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | FABP2 | P12104 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9320686 | 0.83 | PTGS2 (0.50) | BACE1PTGS1MEN1PTGS2KMT2A | |
| SCHEMBL4603480 | 0.82 | BACE1 (0.42) | DHODHBACE1PTGS1MEN1PTGS2 | |
| SCHEMBL16934070 | 0.81 | DHODH (0.42) | DHODHESR2BACE1PTGS1MEN1 | |
| SCHEMBL21199977 | 0.81 | ALOX5AP (0.42) | DHODHBACE1PTGS1MEN1PTGS2 | |
| SCHEMBL4934640 | 0.79 | SENP1 (0.42) | ESR2CYP2C9CYP2C19RPS6KA3 | |
| SCHEMBL25221380 | 0.78 | BACE1 (0.39) | BACE1PTGS1MEN1PTGS2KMT2A | |
| SCHEMBL10985670 | 0.78 | GRIN1 (0.40) | ESR2PTGS1MEN1PTGS2KMT2A | |
| Methane SCHEMBL27625982 | 0.78 | BACE1 (0.39) | DHODHBACE1PTGS1MEN1PTGS2 | |
| SCHEMBL25275054 | 0.78 | BACE1 (0.39) | DHODHBACE1PTGS1MEN1PTGS2 | |
| SCHEMBL3726533 | 0.78 | DHODH (0.43) | DHODHESR2BACE1PTGS1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030149272-A1 | Method for preparing a polyaromatic compound | RHODIA CHIMIE (FR) | 2003-08-07 | — | — | US | claimed |
| US-6590100-B2 | Reacting an aromatic compound bearing a leaving group and an arylboronic acid and/or its derivatives in the presence of a base and an effective amount of a nickel catalyst | RHODIA CHIMIE (FR) | 2003-07-08 | — | — | US | claimed |
| US-20020173652-A1 | Process for preparing a polyaromatic compound | SHASUN PHARMA SOLUTIONS, INC. | 2002-11-21 | — | — | US | claimed |
| US-4870097-A | ANALGESICS, CENTRAL NERVOUS SYSTEM DISORDERS | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1989-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020173652-A1 | Process for preparing a polyaromatic compound | PAH, ALK, ITPA | DHODH 594/4885ESR2 2977/4885BACE1 3508/4885 |
| US-20030149272-A1 | Method for preparing a polyaromatic compound | PCNA, PAH, AOC1 | DHODH 497/4885ESR2 3024/4885BACE1 2499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.