Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7078648 | 0.89 | FNTA (0.54) | HSD11B1KMT2AMAPK1FNTAFNTB | |
| SCHEMBL7073742 | 0.87 | KMT2A (0.45) | HSD11B1KMT2APOLBFNTAFNTB | |
| SCHEMBL7136223 | 0.83 | KMT2A (0.42) | HSD11B1KMT2AMAPK1FNTAFNTB | |
| SCHEMBL7079158 | 0.82 | SMN1; SMN2 (0.43) | KMT2APOLBMAPTHPGDALDH1A1 | |
| SCHEMBL7073376 | 0.81 | ALDH1A1 (0.46) | HSD11B1KMT2ACA12CA9CA14 | |
| SCHEMBL7073310 | 0.80 | NFE2L2 (0.49) | KMT2AMAPK1MAPTALDH1A1MEN1 | |
| SCHEMBL7073308 | 0.80 | NFE2L2 (0.49) | KMT2AMAPK1MAPTALDH1A1MEN1 | |
| SCHEMBL7079059 | 0.79 | ALDH1A1 (0.45) | HSD11B1KMT2APOLBFNTAFNTB | |
| SCHEMBL7079124 | 0.79 | ALDH1A1 (0.45) | HSD11B1KMT2APOLBFNTAFNTB | |
| SCHEMBL7077837 | 0.77 | ALDH1A1 (0.45) | KMT2APKMCA12CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003059872-A1 | AVB3 AND AVB5 INTEGRIN ANTAGONISTS AND METHODS OF TREATING DISEASES OR CONDITIONS ASSOCIATED WITH AVB3 AND AVB5 INTEGRINS | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-07-24 | — | — | WO | disclosed |