Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7077874 | 0.86 | F2 (0.46) | SMN1; SMN2ALDH1A1F2F10PRSS1 | |
| SCHEMBL7073310 | 0.85 | NFE2L2 (0.49) | SMN1; SMN2ALDH1A1MEN1KMT2ACYP2C19 | |
| SCHEMBL7073308 | 0.85 | NFE2L2 (0.49) | SMN1; SMN2ALDH1A1MEN1KMT2ACYP2C19 | |
| SCHEMBL7078057 | 0.82 | HSD11B1 (0.48) | SMN1; SMN2ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL7078648 | 0.82 | FNTA (0.54) | SMN1; SMN2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL7077585 | 0.81 | F2 (0.41) | ALDH1A1F2F10PRSS1KMT2A | |
| SCHEMBL7073742 | 0.79 | KMT2A (0.45) | SMN1; SMN2ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL7073376 | 0.77 | ALDH1A1 (0.46) | ALDH1A1F2F10PRSS1KMT2A | |
| SCHEMBL7073328 | 0.77 | ALDH1A1 (0.40) | L3MBTL1ALDH1A1F2F10PRSS1 | |
| SCHEMBL7074301 | 0.77 | AOC3 (0.39) | SMN1; SMN2HTTALDH1A1F2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003059872-A1 | AVB3 AND AVB5 INTEGRIN ANTAGONISTS AND METHODS OF TREATING DISEASES OR CONDITIONS ASSOCIATED WITH AVB3 AND AVB5 INTEGRINS | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-07-24 | — | — | WO | disclosed |