Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 2/20 | 0.42 |
| ▸ | PLK1 | P53350 | 5/20 | 0.42 |
| ▸ | PLK3 | Q9H4B4 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7164154 | 0.91 | SMPD1 (0.45) | HPGDALDH1A1KDM4ECYP1A2CYP2C9 | |
| SCHEMBL7077649 | 0.90 | SMPD1 (0.54) | SMN1; SMN2NPC1RAB9AHPGDKDM4E | |
| SCHEMBL7164226 | 0.88 | ALDH1A1 (0.42) | SMN1; SMN2NPC1RAB9AHPGDALDH1A1 | |
| SCHEMBL7081540 | 0.87 | AKR1C3 (0.58) | SMN1; SMN2MAPTCYP1A2CYP19A1PLK1 | |
| SCHEMBL7083321 | 0.86 | PLK1 (0.54) | SMN1; SMN2NPC1RAB9AHDAC8HDAC1 | |
| SCHEMBL7077448 | 0.86 | PLK1 (0.54) | SMN1; SMN2NPC1RAB9AHDAC8HDAC1 | |
| SCHEMBL7080351 | 0.86 | PLK1 (0.54) | SMN1; SMN2NPC1RAB9AHDAC8HDAC1 | |
| SCHEMBL7080272 | 0.86 | PLK1 (0.54) | SMN1; SMN2NPC1RAB9AHDAC8HDAC1 | |
| SCHEMBL7080267 | 0.86 | PLK1 (0.54) | SMN1; SMN2NPC1RAB9AHDAC8HDAC1 | |
| SCHEMBL7081502 | 0.86 | PLK1 (0.54) | SMN1; SMN2NPC1RAB9AHDAC8HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030162818-A1 | Acylsulfonamide derivative | AJINOMOTO CO. INC. (JP) | 2003-08-28 | — | — | US | disclosed |
| US-6555584-B1 | Acetyl-coa carboxylase inhibitors | AJINOMOTO CO., INC. (JP) | 2003-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162818-A1 | Acylsulfonamide derivative | ACSS2, ACACA, FASN | SMN1; SMN2 1718/4885NPC1 397/4885RAB9A 3579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.