Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.58 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.58 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.58 |
| ▸ | MYC | P01106 | 4/20 | 0.54 |
| ▸ | MAX | P61244 | 3/20 | 0.54 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.45 |
| ▸ | BCL2 | P10415 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | PELP1 | Q8IZL8 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7164154 | 0.88 | SMPD1 (0.45) | AKR1C3AKR1C2AKR1C1PLK1PLK3 | |
| SCHEMBL7078472 | 0.87 | SMN1; SMN2 (0.47) | AKR1C3AKR1C2AKR1C1PLK1PLK3 | |
| SCHEMBL7077649 | 0.87 | SMPD1 (0.54) | PLK1GAAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7164226 | 0.85 | ALDH1A1 (0.42) | AKR1C3AKR1C2AKR1C1PLK1PLK3 | |
| SCHEMBL7077448 | 0.83 | PLK1 (0.54) | PLK1PLK3MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7080272 | 0.83 | PLK1 (0.54) | PLK1PLK3MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7080351 | 0.83 | PLK1 (0.54) | PLK1PLK3MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7083321 | 0.83 | PLK1 (0.54) | PLK1PLK3MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7080267 | 0.83 | PLK1 (0.54) | PLK1PLK3MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7081502 | 0.83 | PLK1 (0.54) | PLK1PLK3MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030191323-A1 | Hypoglycemic agent | AJINOMOTO CO., INC. (JP) | 2003-10-09 | — | — | US | disclosed |
| US-20030162818-A1 | Acylsulfonamide derivative | AJINOMOTO CO. INC. (JP) | 2003-08-28 | — | — | US | disclosed |
| US-6555584-B1 | Acetyl-coa carboxylase inhibitors | AJINOMOTO CO., INC. (JP) | 2003-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162818-A1 | Acylsulfonamide derivative | ACSS2, ACACA, FASN | AKR1C3 228/4885AKR1C2 147/4885AKR1C1 186/4885 |
| US-20030191323-A1 | Hypoglycemic agent | GPR119, IAPP, SLC5A2 | AKR1C3 1038/4885AKR1C2 422/4885AKR1C1 530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.