Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 12/20 | 0.68 |
| ▸ | MMP1 | P03956 | 11/20 | 0.68 |
| ▸ | MMP2 | P08253 | 9/20 | 0.68 |
| ▸ | MMP3 | P08254 | 9/20 | 0.68 |
| ▸ | MMP7 | P09237 | 7/20 | 0.68 |
| ▸ | MMP9 | P14780 | 5/20 | 0.51 |
| ▸ | MMP8 | P22894 | 4/20 | 0.51 |
| ▸ | CXCR3 | P49682 | 3/20 | 0.44 |
| ▸ | UBE2M | P61081 | 1/20 | 0.44 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.43 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | BMP1 | P13497 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7078223 | 0.85 | MMP13 (0.65) | MMP13MMP1MMP2MMP3MMP7 | |
| SCHEMBL7241427 | 0.81 | MMP13 (1.00) | MMP13MMP1MMP2MMP3MMP7 | |
| SCHEMBL6372187 | 0.80 | MMP13 (0.60) | MMP13MMP1MMP2MMP3MMP7 | |
| SCHEMBL7084780 | 0.78 | MMP1 (0.66) | MMP13MMP1MMP2MMP3MMP7 | |
| SCHEMBL7078461 | 0.77 | MMP13 (0.58) | MMP13MMP1MMP2MMP3MMP7 | |
| SCHEMBL6294217 | 0.77 | MMP13 (0.55) | MMP13MMP1MMP2MMP3MMP7 | |
| SCHEMBL7243832 | 0.76 | MMP13 (0.89) | MMP13MMP1MMP2MMP3MMP7 | |
| SCHEMBL7347667 | 0.75 | MMP13 (0.51) | MMP13MMP1MMP2MMP3MMP7 | |
| SCHEMBL7347774 | 0.74 | MMP13 (0.54) | MMP13MMP1MMP2MMP3MMP7 | |
| SCHEMBL7347770 | 0.74 | MMP13 (0.54) | MMP13MMP1MMP2MMP3MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030144292-A1 | Carbocyclic side chain containing, N-substituted metalloprotease inhibitors | PROCTER & GAMBLE COMPANY, THE | 2003-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144292-A1 | Carbocyclic side chain containing, N-substituted metalloprotease inhibitors | MMP2, MMP3, CMA1 | MMP13 20/4885MMP1 6/4885MMP2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.