SCHEMBL7078702

SCHEMBL7078702

CC(=O)CC(=O)Nc1cc(C(=O)O)ccc1C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.51
ALDH1A1 P00352 4/20 0.51
KMT2A Q03164 2/20 0.51
MEN1 O00255 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
AKR1C3 P42330 4/20 0.48
AKR1C2 P52895 4/20 0.48
AKR1B10 O60218 2/20 0.48
AKR1B1 P15121 2/20 0.48
AKR1C4 P17516 2/20 0.48
AKR1C1 Q04828 2/20 0.48
HSD17B10 Q99714 3/20 0.47
HPGD P15428 1/20 0.47
LTB4R Q15722 1/20 0.45
SELL P14151 2/20 0.45
SELP P16109 2/20 0.45
LMNA P02545 1/20 0.45
RAB9A P51151 1/20 0.45
SELE P16581 1/20 0.43
NPC1 O15118 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2558622 0.84 SELL (0.62) KDM4EALDH1A1KMT2AMEN1SELL
SCHEMBL11055197 0.84 KMT2A (0.51) KDM4EALDH1A1KMT2AMEN1SMN1; SMN2
SCHEMBL1304624 0.83 NEU3 (0.54) KDM4EALDH1A1KMT2AMEN1SMN1; SMN2
SCHEMBL2556020 0.83 EP300 (0.51) ALDH1A1KMT2AMEN1LTB4RSELL
SCHEMBL7080579 0.83 MEN1 (0.75) KDM4EALDH1A1KMT2AMEN1SMN1; SMN2
SCHEMBL7530798 0.83 ALDH1A1 (0.57) ALDH1A1KMT2AMEN1HPGDLTB4R
SCHEMBL2558174 0.81 MEN1 (0.56) KDM4EALDH1A1KMT2AMEN1SMN1; SMN2
SCHEMBL7531177 0.80 LTB4R (0.68) ALDH1A1KMT2AMEN1LTB4RLMNA
SCHEMBL11051962 0.79 PDK1 (0.55) KDM4EALDH1A1KMT2AMEN1HPGD
SCHEMBL29437944 0.78 KMT2A (0.73) KDM4EALDH1A1KMT2AMEN1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1146088-B1 Method of producing disazo pigment TOYO INK MFG CO (JP) 2003-07-02 EP disclosed
EP-0952191-B1 Disazo pigment composition, printing ink containing the same and a method for manufacturing the same DAINIPPON INK & CHEMICALS (JP) 2002-07-10 EP disclosed
EP-0823459-B1 Disazo pigment composition and printing ink DAINIPPON INK & CHEMICALS (JP) 2002-04-17 EP disclosed
US-20010041793-A1 Method of producing disazo pigment TOYO INK MFG. CO., LTD. (JP) 2001-11-15 US disclosed
EP-1146088-A1 Method of producing disazo pigment Toyo Ink Manufacturing Co. Ltd. (JP) 2001-10-17 EP disclosed
US-6303762-B1 COUPLING A TETRAZO BENZIDINES AND A MIXTURE OF N-PHENYLACETOACETAMIDES TOYO INK MFG. CO., LTD. (JP) 2001-10-16 US disclosed
EP-0952191-A2 Disazo pigment composition, printing ink containing the same and a method for manufacturing the same DAINIPPON INK AND CHEMICALS, INC. (JP) 1999-10-27 EP disclosed
US-5803962-A Disazo pigment composition and printing ink DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-09-08 US disclosed
EP-0823459-A2 Disazo pigment composition and printing ink DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-02-11 EP disclosed