Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | HTR7 | P34969 | 2/20 | 0.46 |
| ▸ | HTR6 | P50406 | 2/20 | 0.46 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7071917 | 0.83 | KDM1A (0.51) | DRD3HTR2AHTR7HTR6 | |
| SCHEMBL7073064 | 0.82 | HTR1A (0.50) | MEN1KMT2AHRH3DRD3HTR2A | |
| SCHEMBL7074984 | 0.81 | MC4R (0.44) | — | |
| SCHEMBL7136992 | 0.79 | FAAH (0.45) | DRD3 | |
| SCHEMBL7075390 | 0.79 | OPRL1 (0.43) | MEN1KMT2ADRD3DRD4HTR7 | |
| SCHEMBL7076875 | 0.76 | LTA4H (0.48) | MEN1KMT2AHRH3DRD3HTR2A | |
| SCHEMBL8882719 | 0.76 | HPGD (0.52) | DRD3DRD4 | |
| SCHEMBL7076338 | 0.74 | HRH3 (0.49) | MEN1KMT2AHRH3DRD3HTR2A | |
| SCHEMBL7781788 | 0.73 | SLC18A3 (0.50) | DRD3 | |
| SCHEMBL7781178 | 0.73 | KDM1A (0.45) | DRD3DRD4HTR2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0740658-B1 | N-SUBSTITUTED AZABICYCLOHEPTANE DERIVATIVES USED, FOR EXAMPLE, AS NEUROLEPTICS | ABBOTT GMBH & CO KG (DE) | 2003-07-02 | — | — | EP | disclosed |
| US-5616705-A | N-substituted azabicycloheptane derivatives, their preparation and use | BASF AKTIENGESELLSCHAFT (DE) | 1997-04-01 | — | — | US | disclosed |