Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 10/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 8/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.34 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.34 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.34 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.34 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.34 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.34 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7079009 | 1.00 | CYP11B1 (0.36) | CYP11B1CYP11B2GLATUBB4ATUBB | |
| SCHEMBL2086908 | 0.82 | MEN1 (0.38) | CYP11B1CYP11B2POLBMEN1ALDH1A1 | |
| SCHEMBL2086904 | 0.82 | MEN1 (0.38) | CYP11B1CYP11B2POLBMEN1ALDH1A1 | |
| SCHEMBL18306062 | 0.78 | CYP11B1 (0.35) | CYP11B1CYP11B2GLATUBB4ATUBB | |
| SCHEMBL5779276 | 0.77 | KEAP1 (0.54) | CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL22774579 | 0.77 | KEAP1 (0.54) | CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL5779272 | 0.77 | KEAP1 (0.54) | CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL21174020 | 0.76 | SLC6A12 (0.33) | SLC6A12MEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL10516101 | 0.75 | GLA (0.59) | CYP11B1CYP11B2GLAPOLBALDH1A1 | |
| SCHEMBL28342664 | 0.74 | CYP11B1 (0.55) | CYP11B1CYP11B2GLAPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030232818-A1 | Antibacterial compounds | ABBVIE INC. | 2003-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030232818-A1 | Antibacterial compounds | PGLS, UGT1A1, CASP1 | CYP11B1 826/4885CYP11B2 1525/4885GLA 244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.