Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 14/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 3/20 | 0.47 |
| ▸ | STS | P08842 | 2/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.47 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SHBG | P04278 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12379508 | 0.89 | HSD17B1 (0.80) | HSD17B1ESR1STSESR2AKR1B10 | |
| SCHEMBL7124870 | 0.85 | HSD17B1 (0.64) | HSD17B1KDM4EALDH1A1ESR1STS | |
| SCHEMBL7124873 | 0.85 | HSD17B1 (0.64) | HSD17B1KDM4EALDH1A1ESR1STS | |
| SCHEMBL12966886 | 0.84 | HSD17B1 (0.81) | HSD17B1CA1CA2CA5ACA9 | |
| SCHEMBL12379505 | 0.83 | USP2 (0.64) | HSD17B1KDM4EALDH1A1STSCYP3A4 | |
| SCHEMBL16148802 | 0.83 | STS (0.70) | HSD17B1KDM4EALDH1A1CA1CA2 | |
| SCHEMBL12418539 | 0.82 | HSD17B1 (0.63) | HSD17B1KDM4EALDH1A1STSLMNA | |
| SCHEMBL12593969 | 0.81 | HSD17B1 (0.80) | HSD17B1ESR1STSESR2AKR1B10 | |
| SCHEMBL5682160 | 0.80 | SHBG (0.46) | HSD17B1KDM4EALDH1A1CA1CA2 | |
| SCHEMBL12379604 | 0.79 | HSD17B1 (0.66) | HSD17B1CA2CA9ESR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6670347-B2 | Selective estrogens that show preference for one of the two known estogen receptors | SCHERING AG (DE) | 2003-12-30 | — | — | US | disclosed |
| EP-1322662-A1 | 19-NOR-17 ALPHA-PREGNA-1,3,5 (10)-TRIEN-17 BETA-OLS OF A 21,16 ALPHA-LACTONE RING | Schering AG (DE) | 2003-07-02 | — | — | EP | disclosed |
| US-20020156271-A1 | 19-nor-17alpha-pregna-1,3,5 (10) -trien-17beta-ols with a 21, 16alpha-lactone ring | JENAPHARM GMBH & CO. KG (DE) | 2002-10-24 | — | — | US | disclosed |
| WO-2002026763-A1 | 19-NOR-17α-PREGNA-1,3,5 (10)-TRIEN-17β-OLS OF A 21,16α-LACTONE RING | SCHERING AG (DE) | 2002-04-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020156271-A1 | 19-nor-17alpha-pregna-1,3,5 (10) -trien-17beta-ols with a 21, 16alpha-lactone ring | HSD17B11, CYP17A1, CYP19A1 | HSD17B1 10/4885KDM4E 2818/4885ALDH1A1 738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.