Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.43 |
| ▸ | CIT | O14578 | 2/20 | 0.43 |
| ▸ | SMO | Q99835 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6793585 | 0.90 | SMO (0.49) | CHRNB2CHRNB4CHRNA3CHRNA4TRPV1 | |
| SCHEMBL6793812 | 0.80 | CHRNB2 (0.48) | CHRNB2CHRNB4CHRNA3CHRNA4TRPV1 | |
| SCHEMBL7086952 | 0.78 | PLG (0.53) | CHRNB2CHRNB4CHRNA3CHRNA4ITGB1 | |
| SCHEMBL7087226 | 0.78 | SMO (0.49) | TRPV1SMOLRRK2KDREGLN1 | |
| SCHEMBL7079790 | 0.76 | S1PR1 (0.51) | CHRNB2CHRNB4CHRNA3CHRNA4ITGB1 | |
| SCHEMBL6793989 | 0.75 | TRPV1 (0.48) | TRPV1SMOEGLN1ALDH1A1 | |
| SCHEMBL6795013 | 0.75 | SMO (0.46) | CHRNB2CHRNB4CHRNA3CHRNA4TRPV1 | |
| SCHEMBL6792746 | 0.75 | PTGS1 (0.57) | CHRNB2CHRNB4CHRNA3CHRNA4LMNA | |
| SCHEMBL9602121 | 0.74 | ANPEP (0.58) | CITMEN1ALDH1A1HTTKMT2A | |
| SCHEMBL9590000 | 0.74 | ANPEP (0.58) | CITMEN1ALDH1A1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |