Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 17/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7080263 | 0.84 | HMGCR (0.42) | HMGCRL3MBTL1THRATHRB | |
| SCHEMBL7084572 | 0.82 | HMGCR (0.40) | HMGCRKMT2ATHRATHRB | |
| SCHEMBL15802579 | 0.70 | GABRA1 (0.32) | CYP1A2CYP2C9CYP2C19KMT2ATHRA | |
| SCHEMBL21074678 | 0.70 | HMGCR (0.57) | HMGCR | |
| SCHEMBL15807576 | 0.69 | NLRP3 (0.38) | CYP2C9KMT2ANPSR1 | |
| SCHEMBL15808090 | 0.68 | NLRP3 (0.47) | KMT2ANPSR1 | |
| SCHEMBL7086714 | 0.68 | HMGCR (0.42) | HMGCR | |
| SCHEMBL6451333 | 0.68 | PPARA (0.46) | — | |
| SCHEMBL11267610 | 0.67 | MAOB (0.42) | THRATHRB | |
| SCHEMBL15807636 | 0.67 | KDM4E (0.51) | CYP1A2CYP2C9KMT2ANPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326618-A2 | USE OF ARYL-SUBSTITUTED 1,1-DIPHOSPHONATES FOR THE TREATMENT OF BONE DISEASES | Ilex Oncology Research S.A. (CH) | 2003-07-16 | — | — | EP | claimed |
| WO-2002011704-A2 | USE OF ARYL-SUBSTITUTED 1,1-DIPHOSPHONATES FOR THE TREATMENT OF BONE DISEASES | SYMPHAR S.A. (CH) | 2002-02-14 | — | — | WO | claimed |