Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAALAD2 | Q9Y3Q0 | 4/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.30 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.30 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14102937 | 0.85 | NAALAD2 (0.57) | NAALAD2FOLH1RIMKLA | |
| SCHEMBL13840852 | 0.84 | NAALAD2 (0.42) | NAALAD2FOLH1PLA2G2C | |
| SCHEMBL12145025 | 0.70 | GABRP (0.39) | NAALAD2FOLH1 | |
| SCHEMBL6948576 | 0.70 | GABRP (0.39) | NAALAD2FOLH1 | |
| SCHEMBL7074528 | 0.66 | MEN1 (0.36) | NAALAD2 | |
| SCHEMBL1285166 | 0.66 | TBXAS1 (0.43) | — | |
| SCHEMBL17242863 | 0.65 | GABRP (0.34) | NAALAD2 | |
| SCHEMBL21494737 | 0.64 | FOLH1 (0.64) | NAALAD2FOLH1RIMKLA | |
| SCHEMBL15764481 | 0.64 | ALDH1A1 (0.32) | — | |
| SCHEMBL7413032 | 0.64 | MMP1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758328-B1 | ANTI-CANCER COMPOUNDS CONTAINING CYCLOPENTAQUINAZOLINE RING | BTG INT LTD (GB) | 2003-07-16 | — | — | EP | disclosed |
| US-5747499-A | CYCLOPENTAQUINAZOLINE COMPOUNDS CYCLOPENTAQUINAZOLINE COMPOUNDS | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1998-05-05 | — | — | US | disclosed |
| EP-0758328-A1 | ANTI-CANCER COMPOUNDS CONTAINING CYCLOPENTAQUINAZOLINE RING | BTG INTERNATIONAL LIMITED (GB) | 1997-02-19 | — | — | EP | disclosed |
| WO-1995030673-A1 | ANTI-CANCER COMPOUNDS CONTAINING CYCLOPENTAQUINAZOLINE RING | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1995-11-16 | — | — | WO | disclosed |