Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL94928 | 0.81 | ALDH1A1 (0.53) | OPRM1OPRL1OPRK1ALDH1A1CYP2C9 | |
| SCHEMBL1426482 | 0.79 | ALDH1A1 (0.51) | OPRM1OPRL1OPRK1ALDH1A1CYP2C9 | |
| Propane SCHEMBL9334285 | 0.79 | ALDH1A1 (0.51) | OPRM1OPRL1OPRK1ALDH1A1CYP2C9 | |
| Hydrochloric Acid SCHEMBL9420413 | 0.78 | ALDH1A1 (0.50) | OPRM1OPRL1OPRK1ALDH1A1CYP2C9 | |
| SCHEMBL1639821 | 0.77 | NPSR1 (0.54) | NPSR1ALDH1A1CYP2C9CYP2C19MCOLN3 | |
| SCHEMBL17358736 | 0.74 | HSD11B1 (0.53) | OPRM1OPRL1OPRK1NPSR1ALDH1A1 | |
| SCHEMBL15131577 | 0.71 | NPSR1 (0.59) | OPRM1OPRL1OPRK1NPSR1ALDH1A1 | |
| SCHEMBL21834901 | 0.71 | ALDH1A1 (0.48) | OPRM1OPRL1OPRK1ALDH1A1CYP2C9 | |
| SCHEMBL21292115 | 0.71 | TSHR (0.40) | NPSR1ALDH1A1LMNAHSD11B1 | |
| SCHEMBL64294 | 0.71 | KMT2A (0.48) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1056432-B1 | IMPROVED CATALYTIC POLYMERIZATION ACCELERATOR SYSTEMS | MYCONE DENTAL SUPPLY COMPANY I (US) | 2003-07-09 | — | — | EP | disclosed |