Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 6/20 | 0.55 |
| ▸ | RAB9A | P51151 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.53 |
| ▸ | SCD | O00767 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14009913 | 0.80 | ALDH1A1 (0.67) | ALDH1A1MAPK1HSD17B10NPC1RAB9A | |
| SCHEMBL2586949 | 0.78 | ALDH1A1 (0.65) | ALDH1A1MAPK1HSD17B10NPC1RAB9A | |
| SCHEMBL204726 | 0.78 | NPC1 (0.73) | ALDH1A1MAPK1HSD17B10NPC1RAB9A | |
| SCHEMBL4873251 | 0.76 | ALDH1A1 (0.67) | ALDH1A1MAPK1HSD17B10NPC1RAB9A | |
| SCHEMBL30002927 | 0.76 | ALDH1A1 (0.67) | ALDH1A1MAPK1HSD17B10NPC1RAB9A | |
| SCHEMBL2586952 | 0.75 | ALDH1A1 (0.65) | ALDH1A1MAPK1HSD17B10NPC1RAB9A | |
| SCHEMBL23566380 | 0.73 | NPC1 (0.75) | ALDH1A1MAPK1HSD17B10NPC1RAB9A | |
| SCHEMBL3926899 | 0.71 | NPC1 (1.00) | HSD17B10NPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL8328333 | 0.71 | ALPL (0.64) | ALDH1A1MAPK1HSD17B10NPC1RAB9A | |
| SCHEMBL6507523 | 0.71 | NPC1 (0.62) | ALDH1A1MAPK1HSD17B10NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592439-B1 | AMINOSULFONYL CARBAMATES | WARNER LAMBERT CO (US) | 2003-07-30 | — | — | EP | claimed |