SCHEMBL7080964

SCHEMBL7080964

CC(C)(C)OC(=O)ON1CCC(c2ccc(CO)cc2)C(OCc2ccc3ccccc3c2OCOCC[Si](C)(C)C)C1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
REN P00797 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7080218 0.91 REN (0.30) REN
SCHEMBL7081179 0.87 REN (0.46) REN
SCHEMBL7079646 0.86 REN (0.34) REN
SCHEMBL6042683 0.86 REN (0.34) REN
SCHEMBL7077071 0.81 REN (0.34) REN
SCHEMBL7080086 0.81 REN (0.31) REN
SCHEMBL7083552 0.81 REN (0.33) REN
SCHEMBL7082266 0.81 REN (0.38) REN
SCHEMBL7082322 0.81 REN (0.33) REN
SCHEMBL7076953 0.80 REN (0.31) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0863875-B1 NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY HOFFMANN LA ROCHE (CH) 2003-06-04 EP disclosed