⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7104643 | 0.87 | — | — | |
| SCHEMBL9386678 | 0.84 | NLRP3 (0.47) | — | |
| SCHEMBL7082105 | 0.84 | NLRP3 (0.50) | — | |
| SCHEMBL7567431 | 0.81 | NLRP3 (0.62) | — | |
| SCHEMBL7084807 | 0.80 | — | — | |
| SCHEMBL13296144 | 0.79 | — | — | |
| SCHEMBL9708149 | 0.78 | — | — | |
| SCHEMBL8962422 | 0.76 | LMNA (0.44) | — | |
| SCHEMBL7080904 | 0.75 | LMNA (0.43) | — | |
| SCHEMBL7567348 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592439-B1 | AMINOSULFONYL CARBAMATES | WARNER LAMBERT CO (US) | 2003-07-30 | — | — | EP | disclosed |
| EP-0592439-A1 | AMINOSULFONYL CARBAMATES | WARNER-LAMBERT COMPANY (US) | 1994-04-20 | — | — | EP | disclosed |
| WO-1992008693-A1 | AMINOSULFONYL CARBAMATES | WARNER-LAMBERT COMPANY (US) | 1992-05-29 | — | — | WO | disclosed |