SCHEMBL9620179

SCHEMBL9620179

CCCOc1cc(N=C=O)c(F)cc1Cl

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPOX P50336 3/20 0.42
CSNK2A1 P68400 2/20 0.39
MCOLN3 Q8TDD5 1/20 0.34
GLA P06280 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ALDH1A1 P00352 3/20 0.33
HPGD P15428 3/20 0.33
CYP3A4 P08684 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
FABP4 P15090 1/20 0.32
HTT P42858 2/20 0.32
RECQL P46063 1/20 0.32
THRA P10827 1/20 0.32
THRB P10828 1/20 0.32
MEN1 O00255 2/20 0.32
MAPT P10636 2/20 0.32
KMT2A Q03164 2/20 0.32
SCN9A Q15858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10574907 0.93 GLA (0.41) PPOXCSNK2A1GLASMN1; SMN2ALDH1A1
SCHEMBL9836317 0.88 PPOX (0.40) PPOXSMN1; SMN2ALDH1A1HPGDCYP3A4
SCHEMBL8599225 0.86 PPOX (0.40) PPOXCSNK2A1MCOLN3GLASMN1; SMN2
SCHEMBL8887423 0.82 NR1I2 (0.39) ALDH1A1HPGDCYP3A4TDP1
SCHEMBL7003782 0.80 ALDH1A1 (0.47) PPOXSMN1; SMN2ALDH1A1HPGDCYP3A4
SCHEMBL7081041 0.80 LMNA (0.41) HPGDHTT
SCHEMBL8600619 0.80 SMN1; SMN2 (0.42) PPOXCSNK2A1GLASMN1; SMN2ALDH1A1
SCHEMBL9533072 0.79 PPOX (0.43) PPOXNPC1RAB9A
SCHEMBL9530045 0.79 LMNA (0.57) PPOXSMN1; SMN2ALDH1A1HPGDTDP1
SCHEMBL8603664 0.78 SMN1; SMN2 (0.40) PPOXGLASMN1; SMN2ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5100457-A OXAZOLIDINEDIONE COMPOUNDS, THE PROCESS FOR PREPARING THE SAME AND HERBICIDAL COMPOSITION CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1992-03-31 US disclosed
EP-0382884-A1 Oxazolidinedione compounds, the process for preparing the same and herbicidal composition containing the same SAGAMI CHEMICAL RESEARCH CENTER (JP) 1990-08-22 EP disclosed
CN-87105777-A Heterogeneous ring compound 1988-04-06 CN disclosed
EP-0255047-A1 3-Aryl uraciles and their use as herbicides CIBA-GEIGY AG (CH) 1988-02-03 EP disclosed
US-4622063-A 4-(2-fluoro-4-halo-5-substituted phenyl)urazols, and herbicidal use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-11-11 US disclosed
US-4593094-A INTERMEDIATES FOR HERBICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-06-03 US disclosed
EP-0075267-B1 4-(2-FLUORO-4-HALO-5-SUBSTITUTED PHENYL)URAZOLS, AND THEIR PRODUCTION AND USE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-01-15 EP disclosed
US-4452981-A HERBICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-06-05 US disclosed
EP-0075267-A1 4-(2-Fluoro-4-halo-5-substituted phenyl)urazols, and their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-03-30 EP disclosed