Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.30 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27626616 | 0.67 | MAOA (0.56) | MAPTSMN1; SMN2MAOAMAOBALDH1A1 | |
| SCHEMBL21539403 | 0.66 | — | — | |
| SCHEMBL1879526 | 0.65 | MAOA (0.48) | MAPTMAOAMAOBALDH1A1HSD17B3 | |
| SCHEMBL10525293 | 0.62 | MAOA (0.50) | MAPTSMN1; SMN2MAOAMAOBALDH1A1 | |
| Biphenyl SCHEMBL28097179 | 0.62 | ALDH1A1 (0.69) | MAPTSMN1; SMN2ALDH1A1BACE1MAPK1 | |
| Biphenyl SCHEMBL27463778 | 0.61 | SMN1; SMN2 (0.64) | MAPTSMN1; SMN2ALDH1A1KDM4ENPC1 | |
| SCHEMBL26118035 | 0.61 | ALDH1A1 (0.47) | MAPTMAOAMAOBALDH1A1BACE1 | |
| Biphenyl SCHEMBL27303985 | 0.59 | SMN1; SMN2 (0.61) | MAPTSMN1; SMN2ALDH1A1MAPK1NPC1 | |
| Biphenyl SCHEMBL2901532 | 0.59 | SMN1; SMN2 (0.61) | MAPTSMN1; SMN2ALDH1A1CYP1A2KDM4E | |
| SCHEMBL5531506 | 0.59 | BACE1 (0.64) | MAPTMAOAMAOBALDH1A1HSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0984973-B1 | STEREORIGID METALLOCENE COMPOUNDS | BASELL POLYOLEFINE GMBH (DE) | 2003-07-23 | — | — | EP | disclosed |
| US-6410661-B1 | POLYMERIZATION CATALYST | BASELL POLYOLEFINE GMBH (DE) | 2002-06-25 | — | — | US | disclosed |
| EP-0984973-A1 | STEREORIGID METALLOCENE COMPOUNDS | Basell Polyolefine GmbH (DE) | 2000-03-15 | — | — | EP | disclosed |
| WO-1998050395-A1 | STEREORIGID METALLOCENE COMPOUNDS | TARGOR GMBH (DE) | 1998-11-12 | — | — | WO | disclosed |