SCHEMBL1879526

SCHEMBL1879526

O=C1C=CC=C(c2ccccc2)C1=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.48
MAOB P27338 1/20 0.48
BACE1 P56817 6/20 0.46
PTPN1 P18031 5/20 0.45
PTPRC P08575 3/20 0.45
PTPRF P10586 1/20 0.45
CDC25B P30305 1/20 0.45
HSD17B3 P37058 1/20 0.45
PDE4B Q07343 2/20 0.39
LMNA P02545 2/20 0.37
MAPT P10636 2/20 0.37
HTT P42858 1/20 0.37
ELAVL1 Q15717 2/20 0.37
ALDH1A1 P00352 2/20 0.35
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
BCHE P06276 1/20 0.35
POLB P06746 1/20 0.35
THRB P10828 1/20 0.35
PKM P14618 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27999658 0.96 HSD17B3 (0.52) MAOAMAOBBACE1PTPN1PTPRC
SCHEMBL27626616 0.88 MAOA (0.56) MAOAMAOBBACE1PTPN1PTPRC
SCHEMBL10525293 0.83 MAOA (0.50) MAOAMAOBBACE1PTPN1PTPRC
SCHEMBL5531506 0.78 BACE1 (0.64) MAOAMAOBBACE1PTPN1PTPRC
SCHEMBL28097687 0.74 MEN1 (0.38) MAOAMAOBPTPN1PTPRCCDC25B
SCHEMBL6915646 0.72 APP (0.43) MAOAMAOBHSD17B3MAPTALDH1A1
SCHEMBL28403132 0.70 ALDH1A1 (0.36) MAOAMAOBBACE1HSD17B3ALDH1A1
SCHEMBL28701271 0.70 TAAR1 (0.40) MAOBPTPN1LMNAALDH1A1HPGD
SCHEMBL3883020 0.68
SCHEMBL3885051 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 226 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118056564-A Application of biphenyl dione derivatives in preparation of medicines for preventing and treating viral infection 中国医学科学院药物研究所 2024-05-21 CN claimed
CN-111108443-B Electrophotographic photoreceptor, method for producing the same, and electrophotographic apparatus 富士电机株式会社 2024-01-02 CN claimed
CN-111108443-A Electrophotographic photoreceptor, method for producing electrophotographic photoreceptor, and electrophotographic apparatus 富士电机株式会社 2020-05-05 CN claimed
CN-102809559-B Method for detecting halogenated aromatic organic matter RES CT ECO ENVIRONMENTAL SCIEN 2015-06-17 CN claimed
CN-102809559-A Method for detecting halogenated aromatic organic matter RES CT ECO ENVIRONMENTAL SCIEN 2012-12-05 CN claimed
US-20250197427-A1 ORGANIC COMPOUNDS AND DISPLAY PANELS WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2025-06-19 US disclosed
CN-114665037-B Carrier transport layer structure and thin film light emitting diode containing the same 华南理工大学 2025-05-16 CN disclosed
US-20250057043-A1 ORAGNIC COMPOUNDS, MIXTURES, COMPOSITIONS, LIGHT-EMITTING ELEMENTS, AND DISPLAY PANELS SHENZHEN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2025-02-13 US disclosed
CN-116003779-B Low molecular weight polyphenyl ether and preparation method thereof 天津大学 2024-12-24 CN disclosed
US-20240334818-A1 AROMATIC AMINE COMPOUNDS, AND COMPOSITIONS AND ORGANIC ELECTRONIC DEVICES INCLUDING THE SAME GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) 2024-10-03 US disclosed
US-20240228515-A1 BORON-CONTAINING TRIPHENYLENE COMPOUNDS, COMPOSITIONS, AND ORGANIC ELECTRONIC DEVICES USING THE SAME SHENZHEN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2024-07-11 US disclosed
US-20240224780-A1 Organic Compound, Light-Emitting Element, and Display Panel SHENZHEN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2024-07-04 US disclosed
US-6406823-B2 Photoreceptor and method involving residual voltages XEROX CORPORATION 2002-06-18 US disclosed
CN-1339721-A New bipolar organic light sensitive body XIANLI NEW TECHNOLOGY CO LTD T (CN) 2002-03-13 CN disclosed
CN-1334837-A Process for manufacture of low molecular weight polyphenylene ether resins through redistribution GEN ELECTRIC (US) 2002-02-06 CN disclosed
US-20010001057-A1 Photoreceptor and method involving residual voltages XEROX CORPORATION. 2001-05-10 US disclosed
US-4350628-A OXIDATIVE DEHYDROGENATION WITH A BENZOQUINONE RESEARCH CORPORATION (US) 1982-09-21 US disclosed
US-4283328-A TREATING AN N-BLOCKED AMINO ACID RESIDUE WITH A TETRAMETHYL GUANIDINIUM SALT OF A PEPTIDE CHAIN RESEARCH CORPORATION (US) 1981-08-11 US disclosed
US-4261884-A DESIRABLE BIOLOGICAL PROPERTIES AND STABILITY TO ENZYME CLEAVAGE RESEARCH CORPORATION (US) 1981-04-14 US disclosed
US-3959475-A ANTIDEPRESSANT, TRANQUILIZER, ANALGESIC AMERICAN HOECHST CORPORATION (US) 1976-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240334818-A1 AROMATIC AMINE COMPOUNDS, AND COMPOSITIONS AND ORGANIC ELECTRONIC DEVICES INCLUDING THE SAME ADRA1A, ADRB1, ADRA1D MAOA 86/4885MAOB 103/4885BACE1 84/4885
US-20240228515-A1 BORON-CONTAINING TRIPHENYLENE COMPOUNDS, COMPOSITIONS, AND ORGANIC ELECTRONIC DEVICES USING THE SAME NR0B2, NR0B1, NR2E1 MAOA 3721/4885MAOB 2910/4885BACE1 2365/4885
US-20240224780-A1 Organic Compound, Light-Emitting Element, and Display Panel NR2E3, NR0B2, C5 MAOA 589/4885MAOB 267/4885BACE1 990/4885
US-20250197427-A1 ORGANIC COMPOUNDS AND DISPLAY PANELS CHRM1, CHRM2, C1S MAOA 206/4885MAOB 45/4885BACE1 1119/4885
US-20250057043-A1 ORAGNIC COMPOUNDS, MIXTURES, COMPOSITIONS, LIGHT-EMITTING ELEMENTS, AND DISPLAY PANELS NR2E3, OR10J3, ORC3 MAOA 1926/4885MAOB 1773/4885BACE1 1031/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.