Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | COMT | P21964 | 1/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10936188 | 0.83 | KMT2A (0.68) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL390770 | 0.81 | KMT2A (0.56) | KMT2AKDM4EALOX12CA12CA1 | |
| SCHEMBL8517377 | 0.79 | KMT2A (0.54) | KMT2AKDM4ECA12CA1CA2 | |
| SCHEMBL30908297 | 0.79 | KMT2A (0.59) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL18230355 | 0.79 | KMT2A (0.59) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL7081072 | 0.77 | KDM4E (0.53) | KMT2AKDM4EALOX12COMTNAPRT | |
| SCHEMBL2112972 | 0.77 | COMT (0.49) | KMT2AKDM4EALOX12TTRCA1 | |
| SCHEMBL29564068 | 0.77 | COMT (0.49) | KMT2AKDM4EALOX12TTRCA1 | |
| SCHEMBL28502273 | 0.77 | NFE2L2 (0.43) | KDM4EALOX12COMTNAPRTLMNA | |
| SCHEMBL21061787 | 0.76 | KMT2A (0.56) | KMT2AKDM4ECA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997007100-A1 | PROCESS FOR THE PRODUCTION OF HYDROXYPYRIDINE SULFONIC ACIDS | NOVARTIS AG (CH) | 1997-02-27 | — | — | WO | claimed |
| CN-105088311-B | A kind of aluminium alloy is without nickel environmental protection hole sealing agent | 深圳前海艾丽优科技有限公司 | 2018-07-24 | — | — | CN | disclosed |
| EP-2968342-A1 | COMPOSITIONS COMPRISING THIENOPYRIMIDINE AND THIENOPYRIDINE COMPOUNDS AND METHODS OF USE THEREOF | The Regents Of The University Of Michigan (US) | 2016-01-20 | — | — | EP | disclosed |
| CN-105088311-A | Aluminum alloy nickel-free environment-friendly hole sealing agent | SHENZHEN QIANHAI AILIYOU TECHNOLOGY CO LTD | 2015-11-25 | — | — | CN | disclosed |
| WO-2014164543-A1 | COMPOSITIONS COMPRISING THIENOPYRIMIDINE AND THIENOPYRIDINE COMPOUNDS AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2014-10-09 | — | — | WO | disclosed |
| US-7897635-B2 | HIV protease inhibitors | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2011-03-01 | — | — | US | disclosed |
| CN-101048403-B | Heterocyclic antiviral compounds | HOFFMANN LA ROCHE | 2010-06-16 | — | — | CN | disclosed |
| US-20080075686-A1 | Deodorizer and method for using the same | TOTO LTD. (JP) | 2008-03-27 | — | — | US | disclosed |
| CN-101048403-A | Heterocyclic antiviral compounds | ROCHE PALO ALTO LLC (CH) | 2007-10-03 | — | — | CN | disclosed |
| US-20070082883-A1 | HIV protease inhibitors | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2007-04-12 | — | — | US | disclosed |
| US-7157489-B2 | HIV protease inhibitors | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2007-01-02 | — | — | US | disclosed |
| EP-1485387-A1 | CARBAMATES AS HIV PROTEASE INHIBITORS | BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2004-12-15 | — | — | EP | disclosed |
| US-20040039016-A1 | HIV protease inhibitors | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-02-26 | — | — | US | disclosed |
| WO-2003078438-A1 | CARBAMATES AS HIV PROTEASE INHIBITORS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2003-09-25 | — | — | WO | disclosed |
| WO-1997007100-A1 | PROCESS FOR THE PRODUCTION OF HYDROXYPYRIDINE SULFONIC ACIDS | NOVARTIS AG (CH) | 1997-02-27 | — | — | WO | disclosed |
| WO-1997007100-A1 | PROCESS FOR THE PRODUCTION OF HYDROXYPYRIDINE SULFONIC ACIDS | NOVARTIS AG (CH) | 1997-02-27 | — | — | WO | disclosed |
| CN-1094028-A | Selective PDE enzyme (IV) inhibitor catechol diether class | PFIZER (US) | 1994-10-26 | — | — | CN | disclosed |
| CN-86100895-A | GOLD ELECTROPLATING BATH | — | 1986-07-16 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070082883-A1 | HIV protease inhibitors | SERPINB1, TMPRSS15, DNPEP | KMT2A 3671/4885KDM4E 2514/4885ALOX12 3788/4885 |
| US-20040039016-A1 | HIV protease inhibitors | SERPINB1, TMPRSS15, DNPEP | KMT2A 3671/4885KDM4E 2514/4885ALOX12 3788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.