Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORT1 | Q99523 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KDR | P35968 | 3/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | CSF1R | P07333 | 1/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.49 |
| ▸ | KIT | P10721 | 1/20 | 0.49 |
| ▸ | FLT1 | P17948 | 1/20 | 0.49 |
| ▸ | FLT4 | P35916 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | DGAT2 | Q96PD7 | 3/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | JAK1 | P23458 | 1/20 | 0.47 |
| ▸ | TYK2 | P29597 | 1/20 | 0.47 |
| ▸ | APOB | P04114 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6798808 | 0.90 | KDR (0.56) | NAMPTALDH1A1GAAMAPTKDR | |
| SCHEMBL7160923 | 0.79 | TRPV1 (0.48) | ALDH1A1MAPTKDRMEN1KMT2A | |
| SCHEMBL7086952 | 0.79 | PLG (0.53) | APOBMTTPSMN1; SMN2RXFP1 | |
| SCHEMBL7079790 | 0.79 | S1PR1 (0.51) | APOBMTTPSMN1; SMN2RXFP1 | |
| SCHEMBL6788420 | 0.79 | MTTP (0.57) | NAMPTALDH1A1GAAKDRHDAC1 | |
| SCHEMBL7086824 | 0.79 | LMNA (0.48) | ALDH1A1MAPTKDRJAK2JAK1 | |
| SCHEMBL28752149 | 0.78 | PDE2A (0.48) | SORT1APOBMTTPPDE2ARXFP1 | |
| SCHEMBL7084265 | 0.78 | KMT2A (0.59) | SORT1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6794043 | 0.78 | SMO (0.61) | SORT1GAAKDRAPOBMTTP | |
| SCHEMBL7085005 | 0.78 | MEN1 (0.59) | MEN1KMT2ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |