Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | STAT6 | P42226 | 1/20 | 0.42 |
| ▸ | PARP14 | Q460N5 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12835307 | 0.82 | CYP3A4 (0.60) | CYP2D6KDM4EALDH1A1SMN1; SMN2GLA | |
| SCHEMBL7083102 | 0.81 | CYP2D6 (0.51) | GPR35CYP2D6KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7085772 | 0.81 | CYP3A4 (0.48) | CYP2D6KDM4EALDH1A1GLASTING1 | |
| SCHEMBL7086254 | 0.81 | CYP1A2 (0.58) | CYP2D6KDM4EALDH1A1SMN1; SMN2GLA | |
| SCHEMBL9330744 | 0.81 | CYP1A2 (0.58) | CYP2D6KDM4EALDH1A1SMN1; SMN2GLA | |
| SCHEMBL9526792 | 0.80 | NQO2 (0.53) | GPR35CYP2D6KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL12835507 | 0.80 | ALDH1A1 (0.70) | CYP2D6KDM4EALDH1A1SMN1; SMN2GLA | |
| SCHEMBL12835345 | 0.79 | CYP3A4 (0.52) | CYP2D6KDM4EALDH1A1GLASTING1 | |
| Mitoflaxone SCHEMBL106705 | 0.79 | CYP1A2 (0.62) | CYP2D6KDM4EALDH1A1SMN1; SMN2GLA | |
| SCHEMBL9329003 | 0.77 | CYP1A2 (0.48) | CYP2D6KDM4EALDH1A1SMN1; SMN2GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011023287-A1 | USE OF FAA AND ITS DERIVATIVES IN COSMETICS AND DERMATOLOGY | MERCK PATENT GMBH (DE) | 2011-03-03 | — | — | WO | disclosed |
| EP-1328262-A2 | A METHOD TO INCORPORATE N-(4-HYDROXYPHENYL) RETINAMIDE IN LIPOSOMES | Board of Regents, The University of Texas System (US) | 2003-07-23 | — | — | EP | disclosed |
| US-20020143062-A1 | Method to incorporate N-(4-hydroxyphenyl) retinamide in liposomes | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2002-10-03 | — | — | US | disclosed |
| WO-2002032413-A2 | A METHOD TO INCORPORATE N-(4-HYDROXYPHENYL) RETINAMIDE IN LIPOSOMES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2002-04-25 | — | — | WO | disclosed |
| EP-0341104-B1 | Substituted flavonoid compounds, their salts, their manufacture and medicines containing these materials | MERCK PATENT GMBH (DE) | 1993-12-29 | — | — | EP | disclosed |
| US-5116954-A | Antitumor agents | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1992-05-26 | — | — | US | disclosed |