Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.50 |
| ▸ | PRKDC | P78527 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | STAT6 | P42226 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.43 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.43 |
| ▸ | PSMD12 | O00232 | 1/20 | 0.43 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.43 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7083102 | 0.90 | CYP2D6 (0.51) | NQO2CYP2D6PRKDCMEN1KMT2A | |
| Mitoflaxone SCHEMBL106705 | 0.84 | CYP1A2 (0.62) | CYP2D6PRKDCMEN1KMT2ACYP1A2 | |
| SCHEMBL7083153 | 0.83 | CYP2D6 (0.54) | CYP2D6PRKDCMEN1KMT2ACYP1A2 | |
| SCHEMBL12835503 | 0.81 | CYP1A2 (0.60) | CYP2D6PRKDCMEN1KMT2ACYP1A2 | |
| SCHEMBL9328614 | 0.81 | CYP1A2 (0.59) | CYP2D6PRKDCMEN1KMT2ACYP1A2 | |
| SCHEMBL12835531 | 0.81 | CYP1A2 (0.54) | CYP2D6PRKDCMEN1KMT2ACYP1A2 | |
| SCHEMBL7083117 | 0.81 | CYP1A2 (0.59) | CYP2D6PRKDCCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL7081709 | 0.80 | GPR35 (0.52) | CYP2D6CYP1A2CYP3A4CYP2C19STAT6 | |
| SCHEMBL7085632 | 0.80 | CYP2D6 (0.53) | CYP2D6PRKDCMEN1KMT2ACYP1A2 | |
| SCHEMBL12835629 | 0.79 | CYP2D6 (0.53) | CYP2D6PRKDCMEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0341104-B1 | Substituted flavonoid compounds, their salts, their manufacture and medicines containing these materials | MERCK PATENT GMBH (DE) | 1993-12-29 | — | — | EP | disclosed |