Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5708840 | 0.79 | MAPT (0.48) | MAPTALDH1A1LMNATP53HPGD | |
| SCHEMBL5708846 | 0.72 | TXNRD1 (0.49) | ALDH1A1LMNAHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL5708902 | 0.72 | ALDH1A1 (0.62) | MAPTNPC1ALDH1A1LMNATP53 | |
| SCHEMBL6849909 | 0.64 | — | — | |
| SCHEMBL5708816 | 0.62 | TXNRD1 (0.51) | MAPTALDH1A1LMNAHPGDHTT | |
| SCHEMBL29374862 | 0.62 | MAPT (0.57) | MAPTNPC1ALDH1A1LMNATP53 | |
| SCHEMBL11523233 | 0.62 | GRIN2D (0.41) | MAPTALDH1A1HPGDKMT2AL3MBTL1 | |
| SCHEMBL300103 | 0.61 | GAA (0.59) | MAPTNPC1ALDH1A1LMNATP53 | |
| SCHEMBL5708797 | 0.61 | ALDH1A1 (0.48) | MAPTNPC1ALDH1A1LMNATP53 | |
| SCHEMBL5708726 | 0.61 | KMT2A (0.47) | MAPTALDH1A1HPGDKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030070239-A1 | Agent and method for dyeing keratin fibers | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-04-17 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030070239-A1 | Agent and method for dyeing keratin fibers | KRT18, AOC1, S100B | MAPT 2273/4885NPC1 4185/4885ALDH1A1 87/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.