Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7088314 | 0.77 | LMNA (0.35) | KMT2AALDH1A1GAALMNAACLY | |
| SCHEMBL7088315 | 0.73 | LMNA (0.34) | KMT2AALDH1A1GAALMNA | |
| SCHEMBL7081979 | 0.73 | ACLY (0.38) | ALDH1A1GAACA2ACLY | |
| SCHEMBL9423113 | 0.70 | ACLY (0.38) | ALDH1A1GAALMNAACLYTSHR | |
| SCHEMBL9423209 | 0.70 | ACLY (0.36) | ALDH1A1GAACA1CA2ACLY | |
| SCHEMBL7085512 | 0.69 | GAA (0.36) | KMT2AALDH1A1GAALMNA | |
| SCHEMBL9423213 | 0.69 | DUT (0.36) | MEN1KMT2AALDH1A1ACLY | |
| SCHEMBL9423211 | 0.68 | HTT (0.33) | ALDH1A1GAACA1CA2ACLY | |
| SCHEMBL7082216 | 0.68 | DUT (0.34) | ALDH1A1GAAACLY | |
| SCHEMBL7085483 | 0.68 | ACLY (0.38) | ACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592439-B1 | AMINOSULFONYL CARBAMATES | WARNER LAMBERT CO (US) | 2003-07-30 | — | — | EP | claimed |