Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7088314 | 0.88 | LMNA (0.35) | GAALMNAALDH1A1KMT2A | |
| SCHEMBL7088315 | 0.85 | LMNA (0.34) | GAALMNAALDH1A1KMT2A | |
| SCHEMBL16403447 | 0.69 | NPSR1 (0.40) | LMNAALDH1A1KMT2A | |
| SCHEMBL7082210 | 0.69 | MEN1 (0.38) | GAALMNAALDH1A1KMT2A | |
| SCHEMBL27561963 | 0.69 | LMNA (0.42) | GAALMNAALDH1A1KMT2A | |
| SCHEMBL1788903 | 0.68 | ESR1 (0.39) | GAALMNAALDH1A1KMT2A | |
| SCHEMBL9423113 | 0.68 | ACLY (0.38) | GAALMNAALDH1A1 | |
| SCHEMBL9423209 | 0.67 | ACLY (0.36) | GAAALDH1A1 | |
| SCHEMBL7085511 | 0.67 | LMNA (0.37) | LMNAKMT2A | |
| SCHEMBL1788904 | 0.67 | ESR1 (0.38) | GAALMNAALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592439-B1 | AMINOSULFONYL CARBAMATES | WARNER LAMBERT CO (US) | 2003-07-30 | — | — | EP | claimed |
| EP-0592439-B1 | AMINOSULFONYL CARBAMATES | WARNER LAMBERT CO (US) | 2003-07-30 | — | — | EP | disclosed |